Table of Contents
Can midazolam given subcutaneously?
Midazolam is the recommended benzodiazepine for subcutaneous use. Patients on oral benzodiazepines should be converted to midazolam if a benzodiazepine is to be used in a continuous subcutaneous infusion (CSCI).
Can you inject midazolam?
Midazolam injection is used before medical procedures and surgery to cause drowsiness, relieve anxiety, and prevent any memory of the event. It is also sometimes given as part of the anesthesia during surgery to produce a loss of consciousness.
Can diazepam be given IM?
Diazepam Injection BP may be given IV injection, IM injection, or by IV infusion. The absorption from IM injection of diazepam may be variable, particularly for the gluteal muscles, and therefore the IM route of administration should only be used if IV administration is not possible.
Can diazepam be given subcutaneously?
Medications contraindicated for use via subcutaneous infusion due to severe localised reactions3,11: prochlorperazine (Stemetil, an antiemetic); diazepam (Valium, an anxiolytic); and. chlorpromazine (Largactil, an antipsychotic)
Can midazolam be given IM?
Conclusion: Both forms of midazolam, IM and IV, are effective and safe for paediatric sedation in ED. Although the sedative with IV form might appear sooner, IM form of midazolam can be effectively used in patient with limited IV access. Patients are better to observe closely for psychological side-effects.
Can you give midazolam Subcut?
Midazolam injection can be administered via the buccal, sublingual or intranasal route.
Can propofol be given IM?
Conclusions and clinical relevance: One hundred percent propofol is neither safe nor effective when administered via the IM route; presumably as a result of poor systemic uptake of the hydrophobic drug.
How do you give a propofol injection?
For induction of anaesthesia Propofol should be titrated (approximately 20 – 40 mg propofol every 10 seconds) against the response of the patient until clinical signs show the onset of anaesthesia. Most adult patients aged less than 55 years are likely to require 1.5 to 2.5 mg propofol/kg body weight.
What is the antidote for midazolam?
Conclusion: Flumazenil in a dose of 0.15 mg is a safe drug that reverses the sedative effect of midazolam.
How do you dilute diazepam injections?
However, if in some circumstances it is necessary to administer diazepam as an infusion, it is recommended that it be diluted in dextrose 5% in water, normal saline, Ringer’s injection or lactated Ringer’s injection to a dilution of at least 1:40 and used within 6 hours or to a dilution of 1:50 and used within 24 hours …
How do we administer diazepam?
Diazepam may be administered intravenously or intramuscularly (deep into the muscle). However, absorption following I.M. administration is slow and erratic; thus, this route of administration should be avoided if possible.