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What does FIGO grade mean?
The International Federation of Gynecology and Obstetrics (FIGO) developed a grading system for endometrial carcinoma. It is based on the percentage of cells in the tumour that grow in sheets (called solid tumour growth) rather than form glands. It may also take into account how abnormal the cells appear.
What does FIGO Grade 2 mean?
International Federation of Gynecology and Obstetrics (FIGO) Grade 2 endometrial endometrioid adenocarcinoma carries a 88% 5-yr survival rate. They are defined by >5% but <50% solid epithelial component. A small subset may display <5% solid growth, but marked nuclear atypia and are designated Grade 2.
How is FIGO stage determined?
FIGO subcategorizes Stage IB endometrial cancer by the grade of tumor, but AJCC does not. Endocervical extension can only be established by fractional curettage or scraping of the cervix submitted as a separate specimen at D and C.
What is FIGO grade 3 endometrioid adenocarcinoma?
FIGO grade 3 endometrioid endometrial carcinoma (EEC) is a heterogenous group of tumors with variable molecular and clinicopathologic characteristics but is treated clinically as a single entity. There is a need for additional objective markers to help guide management.
What does FIGO Grade 3 mean?
We designate a tumor as FIGO grade 3 if the solid areas resemble poorly differentiated nonkeratinizing squamous cell carcinoma.
What does FIGO 3 mean?
What is endometrioid adenocarcinoma FIGO grade 1?
Grades 1 and 2 endometrioid cancers are type 1 endometrial cancers. Type 1 cancers are usually not very aggressive and they don’t spread to other tissues quickly. Type 1 endometrial cancers are thought to be caused by too much estrogen.
What is endometrioid adenocarcinoma Figo grade 1?
What is grade 3 endometrioid adenocarcinoma?
High-risk endometrial cancer Grade 3 tumors are considered high-risk. They often spread to other parts of the body. Uterine papillary serous, clear cell, and carcinosarcoma are three subtypes of endometrial cancer that are considered grade 3.
Is endometrial adenocarcinoma slow growing?
Type 1 and type 2 endometrial cancer They are usually endometrioid adenocarcinomas, and are linked to excess oestrogen in the body. They are generally slow growing and less likely to spread. Type 2 cancers are not linked to excess oestrogen. They are generally faster growing and more likely to spread.
What stage is well-differentiated adenocarcinoma?
Low grade or grade I tumors are well-differentiated. This means that the tumor cells are organized and look more like normal tissue. High grade or grade III tumor cells are poorly differentiated.