Table of Contents
What is etravirine used for?
Etravirine is used along with other medications to treat human immunodeficiency virus (HIV) infection in adults and children 2 years of age and older who no longer benefit from taking other HIV medications. Etravirine is in a class of medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs).
What is Intelence used for?
INTELENCE® (etravirine) is a prescription medicine that is used in combination with other antiretroviral medicines to treat human immunodeficiency virus-1 (HIV-1) infection in adults and children 2 years of age and older who have taken HIV-1 medicines in the past.
When did etravirine come out?
Etravirine was approved in the US and European Union in 2008. Etravirine is marketed by Janssen, a subsidiary of Johnson & Johnson.
When was nevirapine introduced?
Nevirapine was approved in 1996 and was the first non-nucleoside reverse-transcriptase inhibitor available for the treatment of HIV-1 infection.
What is the mechanism of action of etravirine?
Mechanism of Action Etravirine binds directly to reverse transcriptase and blocks the RNA-dependent and DNA-dependent DNA polymerase activities by causing a disruption of the enzyme’s catalytic site. Etravirine does not inhibit the human DNA polymerases alpha, beta, and gamma.
Is etravirine a generic drug?
Amneal’s etravirine is the first generic equivalent of Intelence (Janssen) and is indicated for the treatment of HIV-1 infection in treatment-experienced patients 6 years of age and older.
What happens if a person stop taking Arvs?
If you stop taking your HIV treatment, when these dormant cells wake up, HIV will start to make copies of itself again because there are no longer medications in your body to stop it. To prevent this and stay undetectable, you must continue to take your HIV treatments daily as prescribed by your health care provider.
How is nevirapine taken?
Nevirapine may be taken with or without food, and with water, milk, or soda. If you or your child are taking the oral liquid, shake it gently before use. Use an oral dosing syringe or dosing cup to measure the right dose.
How much does Intelence cost?
The cost for Intelence oral tablet 25 mg is around $389 for a supply of 120 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What is the best time to take your ARVs?
You should start taking HIV treatment as soon as you’re diagnosed. The advantages of taking HIV treatment: Once your viral load is undetectable, you cannot pass on HIV to partners. (It might take up to six months on treatment to become undetectable.)
Is Norvir generic?
Ritonavir (Norvir) is available as a generic medication and may be significantly cheaper compared to the brand version.