Table of Contents
What does it mean if I have CIN 3?
CIN 3 means the full thickness of the cervical surface layer is affected by abnormal cells. CIN 3 is also called carcinoma-in-situ. This sounds like cancer, but CIN 3 is not cervical cancer. Cancer develops when the deeper layers of the cervix are affected by abnormal cells.
Will CIN3 turn into cancer?
CIN 2 lesions often clear up on their own, but can also progress to CIN 3 lesions. CIN 3 is the most severe. It’s a very slow-growing disease, though: fewer than half of CIN 3 lesions will have become cancer within 30 years.
How long does it take for CIN 3 to turn into cancer?
However, it is estimated that 5% of CIN 2 and 12% of CIN 3 cases will progress to invasive cancer if untreated. In general, it takes 10 to 20 years for CIN to progress to cancer, allowing a significant time period for detection and treatment. Progression from CIN to cancer requires persistent HPV infection.
Will CIN 3 come back after LEEP?
Definitely. A few women we spoke interviewed did have a recurrence of abnormal cells after treatment for CIN3, and this was often found at a follow-up appointment. Most were treated again by LLETZ.
What are the chances of CIN 2 returning?
Five-year risks of recurrent CIN2+ after treatment varied both by antecedent screening test result and the histology of the treated lesion. The risk ranged from 5% for CIN2 preceded by HPV-positive/ASC-US or LSIL to 16% for CIN3/AIS preceded by AGC/ASC-H/HSIL+ (p<0.0001).
What is CIN3 cancer?
CIN3 may be referred to as severe dyskaryosis or severe dysplasia. Less commonly, it is called carcinoma-in-situ, though this term is rarely used these days. CIN1, 2 and 3 rarely cause any symptoms, such as pain, discharge or bleeding.
Do most people with CIN3 get cancer after A leep?
Hi I was diagnosed with cin3 in march last year and i then had a leep under general anaesthetic. I was told that 95 per cent of people with cin3 do not go on to have cervical cancer diagnosed after leep. I was one of the unlucky 5 per cent and after further investigations (ct and mri scans) I was diagnosed with 1b1 cervical cancer.
What is the difference between CIN2 and CIN3 grade changes?
CIN3 – indicates more severe changes (not cancer); affecting the full thickness of the surface layer of the cervix. Even with CIN2 or CIN3 grade changes, the cell changes are unlikely to be cancer.
How do you treat cin1 CIN2 and CIN3?
Treatment is usually given to remove CIN2 or CIN3 abnormal cells, also called moderate or severe dyskaryosis or dysplasia (see ‘ Treatments and their impacts’ ). CIN1 – indicates mild changes; affecting only one-third of the thickness of the surface layer of the cervix.