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What is desogestrel 75 microgram used for?
Desogestrel tablets are a POP — a progesterone-only pill — containing the synthetic hormone desogestrel, which stops the female body ovulating, to prevent pregnancy. Desogestrel 75mcg tablets are taken every day without a break and can be taken up to 12 hours late and still continue to be effective as birth control.
What kind of pill is desogestrel?
Desogestrel is used in hormonal contraception in women, specifically in birth control pills. It is used alone in progestogen-only pills (“mini pills”) and in combination with the estrogen ethinylestradiol in combined oral contraceptive pills.
Will desogestrel pill stop periods?
Some disadvantages of the progestogen-only pill include: you may not have regular periods while taking it – your periods may be lighter, more frequent, or may stop altogether, and you may get spotting between periods. it does not protect you against STIs.
Does desogestrel make you tired?
A recent survey of more than 2,000 women found that hormonal contraceptive users had more insomnia symptoms and increased levels of daytime sleepiness. People using progestogen-only methods reported sleeping less in total compared with those on a combined type.
Do you bleed on desogestrel?
Vaginal bleeding of various amounts may occur between your regular menstrual periods during the first 3 months of use. This is sometimes called spotting when slight, or breakthrough bleeding when heavier. If this should occur, continue with your regular dosing schedule. The bleeding usually stops within 1 week.
How long do you bleed on desogestrel?
The bleeding usually stops within 1 week. Check with your doctor if the bleeding continues for more than 1 week. If the bleeding continues after you have been taking hormonal contraceptives on schedule and for more than 3 months, check with your doctor.
Why am I having a period on desogestrel?
Irregular bleeding or spotting is common in the first three to four months after you start taking the pill. This should subside once your body adjusts to the medication. You may experience spotting later on if you’ve missed or skipped a dose. If this bleeding becomes heavy, don’t stop taking your medication.
What is the mechanism of action of desogestrel?
Mechanism of action Desogestrel enters the cell passively and acts by binding selectively to the progesterone receptor and generating low androgenic activity. 8 Its binding produces an effect like a transcription factor and thus, it produces modifications in the mRNA synthesis. 9
Does desogestrel affect ovulation?
Desogestrel main therapeutic effect due to its mechanism of action is known to be related to the inhibition of the ovulation in 97% of the cycles. This effect was proven in clinical trials in non-breastfeeding women from which the Pearl failure rate was reported to be of 0.17 per 100 women-years.
What is desogestrel made of?
Desogestrel is part of the combined oral contraceptives that contain a mix of estrogen and progestin which inhibit ovulation. 12 with evidence-based and structured datasets. Build, train, & validate predictive machine-learning models with structured datasets.
What is the AUC of desogestrel?
The bioavailability of desogestrel is reported to be in the range of 60-80% and the reported AUC is of 3000 ng.h/ml. 14 Almost all the administered dose is modified to the active metabolite, etonogestrel. 7 The apparent volume of distribution of desogestrel is of 1.5 L/kg. 14