Why is Exophthalmic goitre called Graves?
Exophthalmic goitre, also known as Graves disease, is an autoimmune disease. It is a disease related to the thyroid gland and it is caused due to hyperthyroidism. Thyroid glands generally become enlarged and secrete high levels of thyroid hormones.
What is a characteristic symptom of Graves hyperthyroidism?
A fine tremor of the hands or fingers. Heat sensitivity and an increase in perspiration or warm, moist skin. Weight loss, despite normal eating habits. Enlargement of the thyroid gland (goiter)
What causes Graves dermopathy?
Graves’ dermopathy results from a buildup of certain carbohydrates in the skin — the cause of which isn’t known. Carbohydrate buildup also causes the eye problems associated with Graves’ disease. The vast majority of people who develop Graves’ dermopathy also have Graves’ ophthalmopathy.
What is the difference between simple goitre and Exophthalmic goiter?
Simple goitre is caused by Hyposecretion of Thyroxine by the thyroid gland. the symptom is the swollen neck whereas, exophthalmic goiter is caused by the hypersecretion of the thyroid gland. The symptom is the protruding eyeballs.
Is goitre and Exophthalmic goitre same?
Graves disease, also called toxic diffuse goitre or exophthalmic goitre, endocrine disorder that is the most common cause of hyperthyroidism (excess secretion of thyroid hormone) and thyrotoxicosis (effects of excess thyroid hormone action in tissue).
What does thyroid dermopathy look like?
Most common clinical presentation is in the form of nonpitting edema and induration of the skin giving a ‘peau d’orange’ appearance along with occasional raised, hyperpigmented, violaceous papules. Other clinical variants of thyroid dermopathy are plaques, nodules, and had polypoid or elephantiasic type lesions.
Does Graves disease affect your legs?
Detailed musculoskeletal examination revealed widespread and profound muscle tenderness of the common extensors of the forearms, biceps, trapezius, calves and thighs, but no small joint tenderness or loss of range of limb movement.
Which are the two types of goitre what are their causes Shaalaa?
There are 2 main types of goitre:
- diffuse goitre – where the entire thyroid gland swells and feels smooth to the touch.
- nodular goitre – where solid or fluid-filled lumps called nodules develop within the thyroid and make the thyroid gland feel lumpy to touch; the nodules can be single or multiple and may contain fluid.
What is endemic goitre?
Endemic goitre occurs when the prevalence of thyroid enlargement in the population of an area exceeds 10%. With few exceptions its cause is iodine deficiency superimposed on other goitrogenic factors normally present and responsible for sporadic goitre.
What is the difference between Graves’disease and Basedow syndrome?
The German Karl Adolph von Basedow independently reported the same constellation of symptoms in 1840. As a result, on the European Continent, the terms Basedow syndrome, Basedow disease, or Morbus Basedow are more common than Graves’ disease. Graves’ disease has also been called exophthalmic goiter.
What is the history of Graves’disease?
Graves’ disease owes its name to the Irish doctor Robert James Graves, who described a case of goiter with exophthalmos in 1835. Medical eponyms are often styled nonpossessively; thus Graves’ disease and Graves disease are variant stylings of the same term.
What is another name for Graves’disease?
Graves’ disease has also been called exophthalmic goiter. Less commonly, it has been known as Parry disease, Begbie disease, Flajan disease, Flajani–Basedow syndrome, and Marsh disease. These names for the disease were derived from Caleb Hillier Parry, James Begbie, Giuseppe Flajani, and Henry Marsh.
Which lab tests are performed in the workup of Graves’disease?
Other useful laboratory measurements in Graves’ disease include thyroid-stimulating hormone (TSH, usually undetectable in Graves’ disease due to negative feedback from the elevated T3 and T4), and protein-bound iodine (elevated).