Table of Contents
What is ethyl acetoacetate used for?
ethyl acetoacetate (CH3COCH2COOC2H5), also called acetoacetic ester, an ester widely used as an intermediate in the synthesis of many varieties of organic chemical compounds. Industrially it is employed in the manufacture of synthetic drugs and dyes.
What is the boiling point of ethyl acetoacetate?
357.4°F (180.8°C)Ethyl acetoacetate / Boiling point
What are the hazards chemical safety of ethyl acetoacetate?
May cause adverse health effects if ingested or inhaled. May irritate to skin, eyes and mucous membranes. Used in organic synthesis and in lacquers and paints.
How is acetoacetate made?
Acetoacetate is produced in the mitochondria of the liver from acetoacetyl coenzyme A (CoA). First, another acetyl group is added from acetyl CoA to form 3-hydroxy-3-methylglutaryl CoA, then an acetyl CoA is lost from this, yielding acetoacetate.
Does ethyl acetoacetate dissolve in water?
Thus, we can conclude that due to strong hydrogen bonding in water molecules, the molecules of ethyl acetate do not polarise the water molecules easily. So, ethyl acetate is insoluble in water.
What is an example of active methylene compound?
Reactions. Compounds possessing a methylene bridge located between two strong electron withdrawing groups (such as nitro, carbonyl or nitrile groups) are sometimes called active methylene compounds. Treatment of these with strong bases can form enolates or carbanions, which are often used in organic synthesis.
Is ethyl acetoacetate flammable?
Flammable. ETHYL ACETOACETATE, a beta-keto ester, is more reactive than many esters.
How is acetoacetate used as fuel?
Once acetoacetate is created, it will have one of three fate: (1) It’ll be sent off to other cells and used as fuel, (2) it’ll be converted into a more energy efficient ketone body called BHB and used as energy throughout the body, or (3) it will spontaneously react to create acetone (which is excreted — typically …
What does acetoacetate smell like?
Acetoacetate has a highly characteristic smell, for the people who can detect this smell, which occurs in the breath and urine during ketosis. On the other hand, most people can smell acetone, whose “sweet & fruity” odor also characterizes the breath of persons in ketosis or, especially, ketoacidosis.