What are the intracellular accumulations?
Intracellular accumulations of proteins usually appear as rounded, eosinophilic droplets, vacuoles, or aggregates in the cytoplasm.
Are intracellular accumulations reversible?
The sites of these accumulations are either in the cytoplasm ( phagolysosomes ) and nucleus. Accumulation may be transient and reversible or permanent.
What are the causes of intracellular accumulations?
Causes. Intracellular accumulations may take place by:
What is intracellular accumulation of pigments?
Intra cellular accumulations Pigments. 17. • Pigments are colored substances, some of which are normal constituents of cells (e.g., melanin), whereas others are abnormal and accumulate in cells only under special circumstances – Exogenous – Endogenous. 18. EXOGENOUS ENDOGENOUS 1.
What are the types of cellular adaptation?
Overview: The four basic types of cellular adaptation to be discussed in this section are hyperplasia, hypertrophy, atrophy, and metaplasia.
What is cellular adaptation and its types?
In cell biology and pathophysiology, cellular adaptation refers to changes made by a cell in response to adverse or varying environmental changes. The adaptation may be physiologic (normal) or pathologic (abnormal). Four types of morphological adaptations include atrophy, hypertrophy, hyperplasia, and metaplasia.
What is the single most common cause of cellular injury?
Hypoxia is the most important cause of cell injury. Irreversible cell injury can be recognized by changes in the appearance of the nucleus and rupture of the cell membrane.
Why should you study cell injury?
The study of cell injury and cell death is the basis for the understanding of disease mechanisms. It is interesting and essential material for medical practice and medical science.
What are the causes of cellular injury?
Causes of cell injury
- Oxygen deprivation. A hypoxic state results in reduced aerobic oxidative respiration, which results in cell injury.
- Physical agents.
- Chemical agents and drugs.
- Immunologic reactions.
- Infectious agents.
- Nutritional imbalances.
- Genetic derangement.
- Hypoxia and ischemic cell injury.
What is cellular swelling?
Cellular swelling (synonyms: hydropic change, vacuolar degeneration, cellular edema) is an acute reversible change resulting as a response to nonlethal injuries. It is an intracytoplasmic accumulation of water due to incapacity of the cells to maintain the ionic and fluid homeostasis.
What are extracellular accumulations?
Extracellular matrix accumulation in immune-mediated tubulointerstitial injury. The accumulation of excessive extracellular matrix (ECM) following tubular injury likely represents an imbalance between ECM production and degradation.
What are 5 types of cellular adaptation?
In cell biology and pathophysiology, Cellular adaptation refers to changes made by a cell in response to adverse environmental changes. The adaptation may be physiologic(al) (normal) or pathologic(al) (abnormal). Five major types of adaptation include atrophy, hypertrophy, hyperplasia, dysplasia, and metaplasia.
What are four 4 basic types of cellular adaptation?
What are the 4 types of cellular adaptation?
What are the two causes of cellular injury?
What are the 5 major types of cellular adaptation?
Five major types of adaptation include atrophy, hypertrophy, hyperplasia, dysplasia, and metaplasia.
What are 7 main causes of cell injury?
Oxygen deprivation, Physical agents, Chemical agents and drugs, Immunologic reactions, Infectious agents, Nutritional imbalances, Genetic derangement.
What are the two types of cell injury?
The 2 main types of cell death are necrosis. Ischemic Cell Damage and apoptosis.
Is cellular swelling reversible?
Reversible damage – cellular swelling Cellular swelling (synonyms: hydropic change, vacuolar degeneration, cellular edema) is an acute reversible change resulting as a response to nonlethal injuries.
What are the different types of cellular accumulation?