Table of Contents
What drug contains Diaminopyrimidines?
6.3 Trimethoprim Trimethoprim is one of the recent antibacterial drugs with action on a unique target. It chemically belongs to the group of diaminopyrimidines [101].
What is the drug trimethoprim used for?
Trimethoprim is used to treat infections of the urinary tract. It may also be used for other problems as determined by your doctor. It will not work for colds, flu, or other virus infections. Trimethoprim is available only with your doctor’s prescription.
Why is trimethoprim used as a antibiotic?
Trimethoprim is an antibiotic used to treat bacterial infections. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections.
What is the brand name for trimethoprim?
Trimethoprim is available under the following different brand names: Primsol, Proloprim, and TMP.
What type of drug is trimethoprim?
Trimethoprim is a dihydropyrimidine antimicrobial and antiparasitic agent. It is the prototype of a group of nonsulfonamide drugs that inhibit dihydrofolate reductase in bacterial and protozoal cells. Although introduced as an antimalarial agent, it is now used primarily as an antibacterial agent, especially in combination with sulfamethoxazole.
How does Diaminopyrimidines (trimethoprim) work?
Diaminopyrimidines (Trimethoprim) Mode of action: Inhibition of other metabolic processes. Trimethoprim interferes with folic acid pathway by binding the enzyme dihydrofolate reductase.
What are the side effects of trimethoprim?
Trimethoprim ( TMP) is an antibiotic used mainly in the treatment of bladder infections. Other uses include for middle ear infections and travelers’ diarrhea. With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS. It is taken by mouth. Common side effects include nausea, changes in taste, and rash.
Is trimethoprim a first line antibiotic?
Resistance to trimethoprim is increasing, but it is still a first line antibiotic in many countries. Cultures and susceptibility tests should be done to make sure bacteria are treated by trimethoprim.