Table of Contents
What is ADCP in immunology?
Another major Fc effector function is antibody-dependent cellular phagocytosis (ADCP). ADCP is the mechanism by which antibody-opsonized target cells activate the FcγRs on the surface of macrophages to induce phagocytosis, resulting in internalization and degradation of the target cell through phagosome acidification.
What is ADCC and ADCP?
ADCC: an excess of engaged CD16A induces the release of cytotoxic granules which kill the target [1]. ADCP: an excess of engaged CD32A induces the phagocytosis of the microbe or target cell, thus facilitating antigen presentation and stimulating inflammatory cytokine secretion [2].
How is ADCP triggered?
When a protein complex known as C1q binds the antibody, CDC is induced. This binding triggers the formation of a membrane attack complex that punches holes into the surface of a target cell. In contrast, ADCP relies on macrophages to devour the target cells.
What is ADCP data?
An acoustic Doppler current profiler, or ADCP, is a device that uses sound waves to measure the speed and direction of currents throughout the water column. Understanding how water in the ocean moves provides important information about biological, chemical, and physical properties of the ocean.
What is e t ratio?
Effector (E) to target (T) ratio is defined as ratio of NK cell number to MCF7 cell number, which is usually regarded as an important parameter that affects NK cell cytotoxicity in population-based study.
What is CDC purpose?
As the nation’s health protection agency, CDC saves lives and protects people from health threats. To accomplish our mission, CDC conducts critical science and provides health information that protects our nation against expensive and dangerous health threats, and responds when these arise.
Why an ADCP can be advantageous over other types of flow meters?
ADCP Advantages ADCPs can measure currents remotely. Thus they can record all the action while looking down from a ship or a surface buoy or looking up from a subsurface mounting or mooring. In the latter case, the ADCP is safer from loss due to high drag forces in strong currents.
What does the CDC research?
There are currently four thematic research networks: Cancer Prevention and Control, Managing Epilepsy Well 2.0, Nutrition and Obesity Policy Research and Evaluation, and Physical Activity Policy Research and Evaluation.