What does high uric acid indicate?
If too much uric acid stays in the body, a condition called hyperuricemia will occur. Hyperuricemia can cause crystals of uric acid (or urate) to form. These crystals can settle in the joints and cause gout, a form of arthritis that can be very painful. They can also settle in the kidneys and form kidney stones.
What disease state would result in high uric acid values?
An abnormally high uric acid level has been correlated with gout, hypertension, cardiovascular disease, and renal disease, whereas a reduced uric acid concentration has been linked to multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, and optic neuritis.
Does high uric acid mean kidney failure?
This happens because: the body makes too much uric acid, and/or the kidneys can’t add enough uric acid to your urine, so it builds up in your blood (the more common reason). That’s why having gout and high uric acid may be signs of kidney disease, so if you have gout, get checked for kidney disease.
Does liver produce uric acid?
Uric acid is synthesized mainly in the liver, intestines and the vascular endothelium as the end product of an exogenous pool of purines, and endogenously from damaged, dying and dead cells, whereby nucleic acids, adenine and guanine, are degraded into uric acid.
What causes uric acid to be high?
High uric acid levels in the body can cause crystals of uric acid to form, leading to gout. Some food and drinks that are high in purines can increase the level of uric acid. What is high uric acid level? Uric acid is a waste product found in blood. It’s created when the body breaks down chemicals called purines.
What causes uric acid crystals in gout?
High uric acid levels in the body can cause crystals of uric acid to form, leading to gout. Some food and drinks that are high in purines can increase the level of uric acid.
Where does uric acid go in the body?
Once produced, uric acid is carried in your blood and passes through your kidneys, where most of it is filtered out into the urine. About one in five people has a high uric acid level.
What happens if you have too much uric acid in your body?
If too much uric acid stays in the body, a condition called hyperuricemia will occur. Hyperuricemia can cause crystals of uric acid (or urate) to form. These crystals can settle in the joints and cause gout, a form of arthritis that can be very painful. They can also settle in the kidneys and form kidney stones.