Table of Contents
What are the applications of aldol condensation?
The reaction is commonly used to produce solvents such as alcohol isophorone and diacetone. It works as an intermediate for perfume production. It is also used in pharmaceutical manufacturing, unsaturated ketones and chalcones known as aromatic ketones. Usually, it is used to create plasticizers as well.
What is crossed aldol condensation with example?
Example of Cross Aldol Condensation: The reaction between benzaldehyde and acetophenone undergo cross aldol condensation in presence of dil. NaOH. In this reaction benzaldehyde have no alpha hydrogen but acetophenone have alpha hydrogen so its undergo aldol condensation form β-hydroxy ketone.
What is the main product obtained by the cross aldol condensation?
– In a cross aldol condensation, if one of the molecule is ketone having α- hydrogen and the other is an aldehyde with no α- hydrogen, the product is α,β-unsaturated product and the reaction is called Clasein-Schmidt reaction.
What is cross aldol condensation explain with suitable chemical equations?
Solution. Cross-aldol condensation: When aldol condensation is carried out between two different aldehydes, or two different ketones, or an aldehyde and a ketone, then the reaction is called a cross-aldol condensation. If both the reactants contain α-hydrogens, four compounds are obtained as products.
What are the limitations of aldol condensation?
The aldol condensation is not limited to aldehydes. Ketones may also be used. In fact, it is possible to use two different carbonyl compounds to form a crossed aldol product. One limitation of the crossed aldol reaction is the fact that multiple products can form due to the presence of multiple different α-hydrogen.
Is cross aldol and mixed aldol same?
An aldol reaction between two different carbonyl compounds is called a crossed aldol or mixed aldol reaction. For example, if we mix acetaldehyde and propanal in presence of sodium hydroxide, a crossed aldol reaction is expected to occur with four different products.
Which of the following is not a final product obtained by cross aldol condensation?
3-Methyl-but-2-enal is not a final product obtained by cross aldol condensation of ethanal and propanal.
What is the main condition for aldol condensation?
An aldol condensation is a condensation reaction in organic chemistry in which an enol or an enolate ion reacts with a carbonyl compound to form a β-hydroxyaldehyde or β-hydroxyketone (an aldol reaction), followed by dehydration to give a conjugated enone.
What is crossed Claisen condensation?
A “crossed” Claisen condensation involves the enolate of one ester reacting as a nucleophile with a different (ideally non-enolizable) ester to give a beta-keto ester. When the enolate and ester are on the same molecule, a Claisen condensation will form a ring.
What is the product of aldol condensation reaction?
The product formed for aldol condensation is called β-hydroxy aldehyde or β-hydroxy ketone.
Who discovered aldol condensation?
The aldol reaction, first discovered by Wurtz in 1872,1 is one of the most powerful transformations in organic chemistry. The process unites two carbonyl partners to give β-hydroxyketones with up to two new stereocenters (Scheme 1).
Which of the following is not a final product obtained by the cross aldol condensation of ethanal and propanal?
Which of the following molecule Cannot undergo aldol condensation reaction?
Formaldehyde HCHO does not contain alpha hydrogen atom. Hence, it does not undergo aldol condensation reaction.