What is Claisen condensation used for?
The Claisen Condensation between esters containing α-hydrogens, promoted by a base such as sodium ethoxide, affords β-ketoesters. The driving force is the formation of the stabilized anion of the β-keto ester.
What are the different types of Claisen condensation?
The ‘crossed’ Claisen condensation reaction (also known as mixed Claisen condensation), where one of the molecules is an enolizable ester and the other is a ketone or a non-enolizable ester. The Dieckmann condensation reaction, in which a molecule featuring two ester groups undergoes an intramolecular reaction.
Which of the following esters Cannot undergo a Claisen condensation?
As C6H5- COOC2H5 has no α-hydrogen atom or active methylene group so it cannot undergo Claisen- Condensation reaction.
Which of the esters Cannot undergo Claisen self condensation?
Which of the following esters Cannot undergo Claisen self condensation?
C6H5COOC2H5 cannot undergo self Claisen condensation as it do not has – hydrogen atom.
Which Cannot be used in a Claisen condensation?
LDA is not commonly used in the classic Claisen or Dieckmann condensations due to enolization of the electrophilic ester. The alkoxy portion of the ester must be a relatively good leaving group. Methyl and ethyl esters, which yields methoxide and ethoxide, respectively, are commonly used.
Which of the following ester Cannot undergo?
1 Answer. Explanation: The esters having active methylene group (- CH2 -), show Claisen Condensation reaction. As C6H5- COOC2H5 has no α-hydrogen atom or active methylene group, so it cannot undergo Claisen- Condensation reaction.
Which one of the following esters is obtained by the esterification of propan 2 ol?
Answer: methyl-2-methylpropanoate and water are the products formed.
What esters Cannot undergo a Claisen condensation?
Which of the following esters Cannot give Claisen condensation?
Which of the following will not undergo self condensation?
Formaldehyde HCHO does not contain alpha hydrogen atom. Hence, it does not undergo aldol condensation reaction. Instead, it undergoes Cannizzaro reaction.
What ester is formed from ethanoic acid and propanol?
Answer and Explanation: Ethanoic acid reacts with 1-propanol in the existence of sulfuric acid followed by heating to produce an ester, propyl acetate, and water.
What is an intramolecular Claisen reaction called?
Intramolecular Claisen condensation (or Dieckmann condensation) is a reaction in which an ester is deprotonated at the alpha carbon, generating an enolate, which undergoes an intramolecular nucleophilic attack, yielding a cyclic enol. The enol is protonated with an acid to re-form the beta-keto ester. An enol is a compound with a.
What is an example of condensation reaction?
What is an example of a condensation reaction? Let’s use the condensation of galactose and glucose as an example. Glucose and galactose are both simple sugars – monosaccharides. The result of their condensation reaction is lactose.
What is Claisen Schmidt reaction?
What is the Claisen-Schmidt condensation reaction? The Claisen-Schmidt condensation reaction is an organic reaction in which a ketone or an aldehyde holding an α-hydrogen reacts with an aromatic carbonyl compound which does not have any α-hydrogens. This reaction is named after the chemists J.G. Schmidt and Rainer Ludwig Claisen.
What is the purpose of condensation and hydrolysis reactions?
Salts. A common kind of hydrolysis occurs when a salt of a weak acid or weak base (or both) is dissolved in water.