What is miR in genetics?

What is miR in genetics?

Introduction. MicroRNAs (miRNAs) are a class of evolutionarily conserved, single-stranded non-coding RNA molecules of 19–24 nucleotides that control gene expression at a post-transcriptional level. They derive from the metabolic processing of long RNA transcripts encoded by miR genes.

What is the function of miR 7?

Moreover, the expression of miR-7 is regulated at three levels including gene transcription, process of primary and precursor sequence and formation of mature sequence. Physiologically, miR-7 principally governs the physiological development of Pituitary gland, Optic nervous system and Cerebral cortex.

Is MRI more expensive than CT?

Cost: CT scans are almost half the price of MRIs. The average computed tomography scan costs around $1,200 while an MRI is about $2,000. Speed: CT scans take much less time than MRIs. The exact time required depends on whether you need a contrast dye for the procedure, but MRIs always require more time for the scan.

What is microRNA miR-1?

MicroRNA-1 (miR-1) is a conserved miRNA with high expression in the muscle tissues. In humans, two discrete genes, MIRN1-1 and MIRN1-2 residing on a genomic region on 18q11.2 produce a single mature miRNA which has 21 nucleotides. miR-1 has a regulatory role on a number of genes including heat shock …

Where is miR-1 expressed in a fly?

The fly miR-1 is initially expressed throughout the presumptive mesoderm and continues to be expressed in the larval somatic, visceral, cardiac, and pharyngeal muscles. Muscle-specific transcription factors control miR-1 expression in flies.

What is mimir-1?

MiR-1 has key roles in the development and differentiation of smooth and skeletal muscles.

What is miR-1 hypertrophy?

It is a persistent response of heart to a variety of harmful stimulation, including increased sympathetic nerve activity and pressure load [ 32, 33 ]. Recent studies indicated that aberrant expression of miR-1 plays an important role in the development of cardiac hypertrophy.