What is stromal hyperplasia ovary?
Stromal hyperplasia is the nodular or diffuse proliferation of the ovarian stroma, whereas OHT is stromal proliferation accompanied by luteinised stromal cells [5]. They present with hyperandrogenism, obesity, hyperinsulinaemia, acanthosis nigricans, and even virilization, mainly in postmenopausal women [2].
What causes stromal hyperplasia?
Pseudoangiomatous stromal hyperplasia (PASH) is a rare, benign (noncancerous) breast lesion. It can present as a dense mass which can only sometimes be felt when palpating the breast. That mass is caused by an overgrowth of myofibroblastic cells.
What is ovarian stroma?
The ovarian stroma includes more general components such as immune cells, blood vessels, nerves, and lymphatic vessels, as well as ovary-specific components including ovarian surface epithelium, tunica albuginea, intraovarian rete ovarii, hilar cells, stem cells, and a majority of incompletely characterized stromal …
What is the cortical stroma?
The bulk of the ovary, both cortex and medulla, consists of stroma. Interspersed in the stroma are follicles, which contain oocytes. Ovarian stroma consists of peculiar spindle-shaped stromal cells similar to fibroblasts and arranged into a characteristic whorled texture.
What causes ovarian Hyperthecosis?
Definition – The term ovarian hyperthecosis (OHT) refers to the presence of nests of luteinized theca cells in the ovarian stroma due to differentiation of the ovarian interstitial cells into steroidogenically active luteinized stromal cells (picture 1), causing hyperandrogenism.
What causes Hyperthecosis?
Hyperthecosis occurs when an area of luteinization occurs along with stromal hyperplasia. The luteinized cells produce androgens, which may lead to hirsutism and virilization (or masculinization) in affected women.
What is stromal Hyperthecosis?
The term hyperthecosis refers to the presence of nests of luteinized theca cells in the ovarian stroma due to differentiation of the ovarian interstitial cells into steroidogenically active luteinized stromal cells (picture 1). The result is greater production of androgens.
What are the two zones of ovarian stroma?
The stroma is divided into two zones – an inner medulla and a peripheral cortex.
What is a Luteoma?
Luteoma of pregnancy is a rare, benign condition characterized by a tumor-like mass of the ovary that emerges during pregnancy and regresses spontaneously after delivery. It is usually asymptomatic and the diagnosis is generally incidental.
What is the Rotterdam criteria for PCOS?
According to the Rotterdam criteria, diagnosis requires the presence of at least two of the following three findings: hyperandrogenism, ovulatory dysfunction, and polycystic ovaries.
What’s the difference between hypoplasia and hyperplasia?
Hypoplasia is similar to aplasia, but less severe. It is technically not the opposite of hyperplasia (too many cells). Hypoplasia is a congenital condition, while hyperplasia generally refers to excessive cell growth later in life.
What is the outer layer of the ovary called?
The ovaries are covered on the outside by a layer of simple cuboidal epithelium called germinal (ovarian) epithelium. This is actually the visceral peritoneum that envelops the ovaries. Underneath this layer is a dense connective tissue capsule, the tunica albuginea.
What is stromal content?
Stromal cells, or mesenchymal stromal cells, are differentiating cells found in abundance within bone marrow but can also be seen all around the body. Stromal cells can become connective tissue cells of any organ, for example in the uterine mucosa (endometrium), prostate, bone marrow, lymph node and the ovary.
What is the corona radiata of oocyte?
The corona radiata is an outer layer of follicular (granulosa) cells that form around a developing oocyte in the ovary and remain with it upon ovulation. The underlying zona pellucida (pellucid = “transparent”) is a transparent, but thick, glycoprotein membrane that surrounds the cell’s plasma membrane.
What type of epithelium is present in the ovary?
The ovaries are small almond shaped structures, covered by a thick connective tissue capsule – the tunica albuginea. This is covered by a simple squamous mesothelium called the germinal epithelium.
How to get rid of ovarian cysts?
Diagnosis. A cyst on your ovary can be found during a pelvic exam.
What is treatment for cyst on ovaries?
In premenopausal women,ovarian cysts often resolve on their own within one to two months,without treatment.
How to check for ovarian cancer?
mear tests could be used to detect breast and ovarian cancers early and save thousands of women from disease, researchers have revealed. The revolutionary new approach is potentially able to measure a woman’s risk of developing four cancers or of undetected disease spreading.
How do you treat ovarian cyst?
Ovarian cysts are a common problem in women who are in their menstruating age. They are fluid-filled sacs that form in and on the ovaries. These cysts are usually harmless and cause little or no pain if small. They often disappear on their own. But in the