How do you administer vesicant drugs?
Inject or infuse the vesicant medication through the Y-site needleless connector of a free-flowing I.V. solution, such as 0.9% sodium chloride solution. This additional fluid helps dilute the drug and reduces the risk of vein damage.
What is the safest way to administer a vesicant?
If there is any doubt, don’t use the catheter for vesicant infusions. Prevention is key, as there are no viable or reliable treatments for most vesicant extravasations. The Infusion Nurse Society Standards of Practice mandate that continuous vesicant infusions should be administered through a central venous catheter.
What is a vesicant IV?
A vesicant is any solution or medication capable of causing tissue damage when it enters tissue surrounding the vein.
What is vesicant therapy?
Vesicants are IV solutions and medications that cause ischemia and necrosis. Vesicants are extremely acidic or basic (pH less than 5 or greater than 9), hyperosmolar (extremely concentrated), or vasoconstrictive (cause the blood vessels to constrict). Many chemotherapy drugs are vesicants.
Can Vesicants be given peripherally?
Peripheral vesicants are administered by gravity infusions or i.v. bolus and should not be infused using an infusion pump since the pump may continue to deliver a vesicant into the tissue until the pump alarm is triggered (AIII).
Which route is safest for vesicant drug?
Vincristine (a vinca alkaloid and vesicant) must only be administered intravenously. Sentinel events resulting in permanent disability or death from inadvertent intrathecal administration of vinca alkaloids are well documented.
Can vesicants be given peripherally?
Where is vesicant chemotherapy administered?
Site of administration should be in a large vein away from the extravasation. The first infusion should be initiated as soon as possible and within the first six hours after extravasation. If cooling techniques are being used, withhold cooling 15 minutes before and after the infusion.
Is IV contrast a vesicant agent?
A vesicant is an agent that has the potential to cause blistering or tissue necrosis. Radiologic contrast media are considered to be vesicant solutions.
What does a vesicant do to the human body?
Blister agents or vesicants are chemicals that produce severe irritated skin often resulting in blisters, swelling and inflammation, and general destruction of tissues.
Is CT contrast dye a vesicant?
When administering a vesicant drug as a bolus you should?
If there is more than one vesicant drug, administer DNA binding drugs first followed by non DNA binding drugs e.g. anthracyclines followed by vinca alkaloids. During the administration of a vesicant drug: for bolus infusions staff should remain at the patient’s side during the entire administration.
Is IV contrast a vesicant?
What does the nurse avoid using when administering a vesicant through a peripheral vein?
What IV drugs are vesicants?
Vesicants: Drugs that can result in tissue necrosis or formation of blisters when accidentally infused into tissue surrounding a vein[14]. They include Actinomycin D, Dactinomycin, Daunorubicin, Doxorubicin, Epirubicin, Idarubicin, Mitomycin C, Vinblastine, Vindesine, Vincristine, and Vinorelbine.
What happens if an IV infiltrates?
Elevate the site as much as possible to help reduce swelling.
What is vesicant chemotherapy?
Vesicant chemotherapy is a type of drug that is given during the chemotherapy process and that can cause blistering and swelling at the site of the injection. In extreme cases, a vesicant drug can go into nearby tissues, also known as extravasation, and can cause tissue or skin necrosis, or dead cells.
Is Rocephin IV a vesicant?
Ceftriaxone Rocephin 6.6-6.7 <600 Y Y Y Vesicant / Irritant, one dose daily reduces complications Cefuroxime Zinacef 5.0-8.5 <600 Y Y Y Vesicant / Irritant, thrombophlebitis Ciprofloxacin Cipro IV 3.3-4.6 <600 * N Y Vesicant / Irritant Clindamycin Cleocin 5.5-7.0 <600 Y Y Y Daptomycin Cubicin 4.0-5.0 <600 * N Y