What is Amastigote form of Trypanosoma?
Trypanosoma cruzi, the causative agent of Chagas’ disease assumes two distinct forms in vertebrate hosts: circulating trypomastigote and tissular amastigote. This latter form infects predominantly the myocardium, smooth and skeletal muscle, and central nervous system.
What insect carries Trypanosoma cruzi?
Triatomine bugs are a type of reduviid bug that can carry Trypanosoma cruzi, the parasite that causes Chagas disease.
Where are kissing bugs?
They’re found in Central and South America and Mexico, but they’re heading north. Most of the world’s kissing bugs are in Central and South America and Mexico. They’ve also been found in the United States in the lower 28 states, with higher concentrations in Texas, Arizona and New Mexico.
How is Chagas diagnosed?
The diagnosis of Chagas disease can be made by observation of the parasite in a blood smear by microscopic examination. A thick and thin blood smear are made and stained for visualization of parasites.
Are kissing bugs harmful?
Kissing bugs sometimes have a parasite in their poop that causes Chagas disease. In most people, that causes mild or no symptoms. But in some, the infection can lead to serious, long-term heart problems or disease in the intestines.
Do kissing bugs bite humans?
They’re nicknamed “kissing bugs” for a rather unpleasant reason — they tend to bite people on the face and near the mouth. They can bite people on other parts of the body, too. Kissing bugs carry a parasite called Trypanosoma cruzi. They pick up this parasite by feeding on a person or an animal with a T.
Does the amastigote have a flagellum?
Morphology of L. amazonensis during differentiation of amastigote to promastigote forms. (A) At 0 h, amastigotes have a short flagellum inside the flagellar pocket (arrow).
What is sandfly disease?
Leishmaniasis is a parasitic disease that is found in parts of the tropics, subtropics, and southern Europe. Leishmaniasis is caused by infection with Leishmania parasites, which are spread by the bite of infected sand flies. There are several different forms of leishmaniasis in people.
Are kissing bugs a potential vector of Trypanosoma cruzi?
Abstract Triatomine insects (Hemiptera: Reduviidae), commonly known as kissing bugs, are a potential health problem in the southwestern United States as possible vectors of Trypanosoma cruzi, the causative agent of Chagas disease.
What are Trypanosoma cruzi amastigotes?
Trypomastigotes of T. cruzi are the only stage found circulating in human blood or CSF. In tissue, the parasite forms amastigotes characterized by a single nucleus and kinetoplast. The amastigotes of T. cruzi are morphologically indistinguishable from those of Leishmania spp. Figure A: Trypanosoma cruzi amastigotes in heart tissue.
How do you get Trypanosoma cruzi?
Trypanosoma cruzi is transmitted by kissing bugs (Hemiptera: Reduviidae). The most common genera responsible for transmission of the disease are Triatoma, Rhodnius, and Panstrongylus. Infection usually occurs after bugs defecate on the bite site and are rubbed into the wound by the host scratching.
How is Trypanosoma cruzi diagnosed in blood smears?
Trypanosoma cruzi in thick blood smears stained with Giemsa. Trypansoma cruzi trypomastigotes are the only stage found in the blood of an infected person. Motile circulating trypomastigotes are readily seen on slides of fresh anticoagulated blood in acute infection but are rarely detectable by microscopy in chronic T. cruzi infection.