What is a normal AFP MoM level in pregnancy?

What is a normal AFP MoM level in pregnancy?

Results are given in nanograms per milliliter (ng/mL). Here is the normal range: For adults: less than 40 ng/mL. At 15 to 21 weeks’ gestation: 10 to 150 ng/mL.

What do high levels of alpha-fetoprotein mean in pregnancy?

High levels of AFP may suggest the developing baby has a neural tube defect such as spina bifida or anencephaly. High levels of AFP may also suggest defects with the esophagus or failure of your baby’s abdomen to close. However, the most common reason for elevated AFP levels is inaccurate dating of the pregnancy.

What is a good alpha-fetoprotein level?

An AFP level between 10 ng/mL to 20 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).

What is a normal AFP level at 19 weeks pregnant?

Table II.

AFP, ng/ml Free-β-hCG, mIU/ml
Gestational ages weeks Twin Twin
18 102.4 59,711
19 126.8 42,202
20 136.8 41,172

What is considered a low AFP MoM?

A total of 6,160 gravidas with gestational ages from 14 to 25 weeks were collected to quantify maternal serum alpha-fetoprotein (MSAFP) using an enzyme immunoassay kit. A level over 2.5 MoM (multiples of the median) was defined as high and a level below 0.4 MoM as low.

What is a low AFP in pregnancy?

A positive test with a high AFP suggests a birth defect like spina bifida. That’s typically a result of 2.5 times or more than the “average” level of AFP you’d expect to see at that point in your pregnancy. A positive test with low AFP could mean a problem like Down syndrome or Edwards syndrome.

What causes high levels of alpha fetoprotein?

Hepatocellular carcinoma

  • Metastatic disease affecting the liver
  • Nonseminomatous germ cell tumors
  • Yolk sac tumor
  • What causes elevated AFP levels?

    Help confirm or rule out a diagnosis of liver cancer or cancer of the ovaries or testicles.

  • Monitor cancer treatment. AFP levels often go up if cancer is spreading and go down when treatment is working.
  • See if cancer has returned after treatment.
  • Monitor the health of people with cirrhosis or hepatitis.
  • What is a normal AFP level in pregnancy?

    a lump in the breast or armpit,

  • bloody nipple discharge,
  • inverted nipple,
  • orange-peel texture or dimpling of the breast’s skin (peau d’orange),
  • breast pain or sore nipple,
  • swollen lymph nodes in the neck or armpit,and
  • a change in the size or shape of the breast or nipple.
  • What is the purpose of alpha fetoprotein?

    The purpose of this screening test is to find out which women have a higher risk of having a baby with a birth defect. It is also used to find the women who need additional testing during pregnancy. Without the AFP test, some women would not be given additional testing.