What is the use of Oxamniquine?

What is the use of Oxamniquine?

Oxamniquine is an “antihelmintic,” or anti-worm, medication. It prevents worms from growing or multiplying in your body. Oxamniquine is used only to treat infections caused by the worm Schistosoma mansoni. This is an uncommon infection usually acquired through contact with freshwater in Africa.

What is the trade name for Oxamniquine?

Oxamniquine

Clinical data
Trade names Vansil
AHFS/Drugs.com Micromedex Detailed Consumer Information
Routes of administration By mouth
ATC code P02BA02 (WHO) QP52AA02 (WHO)

What is the mode of action of Oxamniquine?

Oxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release egg. Oxamniquine may associate with an irreversible inhibition of the nucleic acid metabolism of the parasites.

What is the best drug for schistosomiasis?

Praziquantel, a prescription medication, is taken for 1-2 days to treat infections caused by all schistosome species.

What is the chemical makeup of ivermectin?

C₄₇H₇₂O₁₄ (H₂B₁b)Ivermectin / Formula

What are the side effects of praziquantel?

Praziquantel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • not feeling well.
  • headache.
  • dizziness.
  • stomach pain.
  • nausea.
  • fever.
  • itching.

Which injection is used for schistosomiasis?

Currently, the main forms of treatment used for schistosomiasis are praziquantel (PZQ) and oxaminiquine (OXA). PZQ is the drug of choice because it presents as a high-spectrum anthelmintic, used in the treatment of all known species of schistosomiasis and some species of cestodes and trematodes.

How can Schistosoma be controlled?

Schistosomiasis control focuses on reducing disease through periodic, large-scale population treatment with praziquantel; a more comprehensive approach including potable water, adequate sanitation, and snail control would also reduce transmission.

What is the function of praziquantel?

Praziquantel is used to treat schistosoma (infection with a type of worm that lives in the bloodstream) and liver fluke (infection with a type of worm that lives in or near the liver). Praziquantel is in a class of medications called anthelmintics. It works by killing the worms.

What kills Schistosoma?

Schistosomiasis can usually be treated successfully with a short course of a medication called praziquantel, which kills the worms. Praziquantel is most effective once the worms have grown a bit, so treatment may need to be repeated a few weeks after your first dose.