Which cells express NG2?
Neuron-glial antigen 2 (NG2) is a proteoglycan expressed predominantly in oligodendrocyte progenitor cells (OPCs).
What does NG2 mean?
Introduction. Neural/glial antigen 2 (NG2), also known as chondroitin sulfate proteoglycan 4 (CSPG4), is a member of the chondroitin sulfate proteoglycan family, which comprise integral components of the CNS extracellular matrix.
What is ng2 angular?
ng2-admin is a front-end Admin Dashboard template based on Angular, Bootstrap 4 and Angular CLI. That means all the data you can see on graphs, charts and tables is mocked in Javascript so you can use the backend of your choice with no limitations.
Are OPCs stem cells?
In conclusion, these studies suggest that OPCs do not generate a significant number of neurons under normal conditions, and that they are distinct from neural stem cells that reside in the subventricular zone.
Do astrocytes express Olig2?
Recent studies have found that Olig2 is expressed in developing astrocytes and plays a pivotal role in astrocyte development in the brain [7,8,9,10]. These studies indicate that Olig2 acts as a multifaceted transcription factor for some specific cell type differentiation and maturation during neural development.
Can OPCs differentiate into neurons?
Previous studies have shown that OPCs can differentiate into not only oligodendrocytes but also astrocytes and neurons, depending on the area of the brain and stages during CNS development.
Are oligodendrocytes astrocytes?
Among the neuroglia, the two macroglia oligodendrocytes and astrocytes are the most abundant cell types. While the major function of oligodendrocytes is the formation of the lipid-rich myelin structure, the heterogeneous group of astrocytes fulfils a multitude of important roles in cerebral development and homeostasis.
Which chart is best for angular?
10 best Angular chart libraries
- ngx-charts. Ngx-charts is declarative Charting Framework for Angular2 and beyond.
- Angular nvD3. nvD3 is designed to make it easier to work with nvd3.
- ng2-charts. ng2-charts is an Angular charting library based on chart.
- Highcharts.
- Fusion Charts.
- DlChart.
- ngx-f2.
- ng2-google-charts.
What are Oligodendroglia cells?
Oligodendrocytes are the myelinating cells of the central nervous system (CNS). They are the end product of a cell lineage which has to undergo a complex and precisely timed program of proliferation, migration, differentiation, and myelination to finally produce the insulating sheath of axons.
What is the function of the NG2 proteoglycan in the CNS?
In the normal mammalian CNS, the NG2 proteoglycan is expressed by oligodendrocyte precursor cells (OPC) but not by any other neural cell-type. NG2 is a type-1 membrane protein, exerting multiple roles in the CNS including intracellular signaling within the OPC, with effects on migration, cytoskeleton interaction and target gene regulation.
What does NG2 positive mean?
NG2 proteoglycan. NG2-positive cells include oligodendrocyte progenitor cells (OPCs) and other progenitor cell populations, such as chondroblasts, myoblasts, and pericytes, as well as several different tumors including glioblastoma multiforme and melanoma.
What does NG2 do in endothelial cells?
Chondroitin sulfate proteoglycan NG2 is a single-pass type I membrane protein that plays a role in cell proliferation and migration and stimulates endothelial cells motility during microvascular morphogenesis. It is present in neural cells and in extraneural tissues, especially in the developing mesenchyme.
Is there an anti-ng2 chondroitin sulfate proteoglycan antibody?
More>> Anti-NG2 Chondroitin Sulfate Proteoglycan, Cat. No. AB5320, is a rabbit polyclonal antibody that detects rat NG2 Chondroitin Sulfate and is tested for use in Immunohistochemistry and Western Blotting. Less<< MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.