Table of Contents
What is SC in sickle cell?
There are several types of sickle cell disease. The most common are: Sickle Cell Anemia (SS), Sickle Hemoglobin-C Disease (SC), Sickle Beta-Plus Thalassemia and Sickle Beta-Zero Thalassemia.
What are the sickle cell genotypes?
The homozygous hemoglobin S and C (HbSS & HbSC) genotypes result in sickle cell anemia (SCA) whereas heterozygous hemoglobin S and C genotypes (HbAS and HbAC) result in sickle cell trait (SCT).
What is SS in genes?
Hemoglobin SS disease is the most common type of sickle cell disease. It occurs when you inherit copies of the hemoglobin S gene from both parents. This forms hemoglobin known as Hb SS. As the most severe form of SCD, individuals with this form also experience the worst symptoms at a higher rate.
Is sickle cell SC severe?
The anemia in Hb S-C disease is milder than the anemia in sickle cell disease; some patients even have normal hemoglobin levels. , but are usually less frequent and less severe. However, gross hematuria, retinal hemorrhages, and aseptic necrosis of the femoral head are common. Splenomegaly may be present.
What should SC genotype avoid?
avoid very strenuous exercise – people with sickle cell disease should be active, but intense activities that cause you to become seriously out of breath are best avoided. avoid alcohol and smoking – alcohol can cause you to become dehydrated and smoking can trigger a serious lung condition called acute chest syndrome.
What effect does SC genotype have?
People with Hemoglobin SC disease have red blood cells that are differently shaped and therefore do not carry oxygen as effectively. Symptoms of Hemoglobin SC disease include anemia and episodes of fatigue and extreme pain (vaso-occlusive crisis). The severity of the symptoms can vary from person to person.
Is SC a good genotype?
“SC is bad but not the worst genotype in the world since people living with it have a greater chance of survival than those of us that live with SS.
What is a normal sickle cell test?
A sickle cell test looks only for the presence of hemoglobin S, which causes SCD. A negative test is normal. It means your hemoglobin is normal. A positive test result may mean you have sickle cell trait or SCD.
What is sickle cell positive?
Positive result: Indicates that the screening test detected the presence of Hemoglobin S or sickle hemoglobin, which may mean you carry the sickle cell trait. These results are a preliminary screening.