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Is it safe to take terbutaline while pregnant?
[02-17-2011] The U.S. Food and Drug Administration (FDA) is warning the public that injectable terbutaline should not be used in pregnant women for prevention or prolonged treatment (beyond 48-72 hours) of preterm labor in either the hospital or outpatient setting because of the potential for serious maternal heart …
Does terbutaline affect the fetus?
The research suggests that tocolytic terbutaline therapy carries a significant risk for the mother and the child, which can be magnified by extended exposure, sex of the fetus, and administration during critical fetal developmental periods.
Can terbutaline cause fetal tachycardia?
Further, serious fetal adverse effects including fetal tachycardia, hyperinsulinemia, hyperglycemia, myocardial and septal hypertrophy and myocardial ischemia can also occur as result of terbutaline use in a pregnant woman (1-3).
Can terbutaline cause autism?
Terbutaline, a β2-adrenoceptor agonist, is used off-label for long-term management of preterm labor; such use is associated with increased risk of neurodevelopmental disorders, including autism spectrum disorders.
Will terbutaline stop real labor?
Terbutaline injection is sometimes used to stop or prevent premature labor in pregnant women, however, it is not approved by the Food and Drug Administration for this purpose.
Does terbutaline cross placenta?
Terbutaline crossed the placenta rapidly, and fetal plasma levels up to 55% of the maternal plasma levels were found. The conclusion is that this form of administration of terbutaline does not seem to have any negative short-term influences on the fetal carbohydrate metabolism.
Does terbutaline relax the uterus?
Abstract. The uterine and cardiovascular responses to the adrenergic beta2-receptor stimulator terbutaline (TRB) were investigated in 14 patients in normal term labor. TRB, administered intravenously at a rate of 10 to 20 mug per minute, effectively inhibited uterine activity in advanced labor and also expulsion.
Is it safe to use terbutaline in pregnancy?
Terbutaline was been anecdotally successful. Is It Safe to Use Terbutaline in Pregnancy? No, it’s probably not. There are some significant risks that come with its usage. There have been maternal deaths associated with the use of terbutaline for prevention and treatment of preterm labor.
Is terazol safe during pregnancy?
Use is not recommended during the first trimester of pregnancy unless considered essential to patient welfare; this drug may be used during the second and third trimester if the benefit outweighs the risk to the fetus. US FDA pregnancy category: C. See references. Terconazole topical Breastfeeding Warnings
Why is Celestone given during pregnancy?
Why is celestone given during pregnancy? Antenatal Betamethasone and Lung Function Antenatal betamethasone is primarily used to speed up lung development in preterm fetuses. It stimulates the synthesis and release of surfactant (2), which lubricates the lungs, allowing the air sacs to slide against one another without sticking when the infant
Why is Benadryl safe during pregnancy?
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