What is influenza PR8?

What is influenza PR8?

PR8 is a mouse-adapted H1N1 influenza virus that is known to cause severe infection in mice. In contrast, x31 is an H3N2 influenza virus that causes mild to moderate illness in mice, despite containing the six internal genes of PR8.

What are the characteristics of the influenza envelope?

The influenza particle, or virion, is typically spherical, but sometimes filamentous. It has an outer lipid membrane layer called an envelope derived from the host cell that it replicated in. The envelope is covered with glycoproteins HA and NA which form structures like spikes.

What is unique about the influenza virus?

Abstract. Despite 50 years in intense research, influenza remains unique as the only truly pandemic viral infection of humans. In addition, although vaccines against this disease have been developed and used for the past four decades, they remain less effective than those used against other viral infections.

What is on the surface of influenza virus?

The influenza C viruses have only one major surface glycoprotein, the hemagglutinin-esterase-fusion (HEF) protein, which corresponds functionally to the HA and NA of influenza A and B viruses, and one minor envelope protein, CM2 [1].

What is influenza Wikipedia?

Influenza, commonly known as “the flu”, is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue.

Which of the following are characteristics of influenza virus?

A clinical characteristic of human influenza is a sudden rise in body temperature to >38.5 °C 1–3 days following infection. Other symptoms include headache, limb ache, tiredness, general faintness and dry cough.

What is the basic structure of an influenza virus?

The structure of the influenza virus (see Figure 1) is somewhat variable, but the virion particles are usually spherical or ovoid in shape and 80 to 120 nanometers in diameter. Sometimes filamentous forms of the virus occur as well, and are more common among some influenza strains than others.

Which type of influenza is most virulent?

The subtypes H5 and H7 are the most deadly, while the H9 subtype is less dangerous.

What is the basic structure of influenza virus?

Influenza A viruses (IAVs) constitute a major threat to human health. The IAV genome consists of eight single-stranded viral RNA segments contained in separate viral ribonucleoprotein (vRNP) complexes that are packaged together into a single virus particle.

Is influenza virus RNA or DNA?

-stranded RNA
All influenza viruses consist of single-stranded RNA as opposed to dual-stranded DNA. The RNA genes of influenza viruses are made up of chains of nucleotides that are bonded together and coded by the letters A, C, G and U, which stand for adenine, cytosine, guanine, and uracil, respectively.

What are the properties of virus?

General Properties of Viruses

• Nucleic acid -contains 3-400 genes. Deoxyribonucleic Acid (DNA) -unique features.
• Capsid -The capsid accounts for most of the virion mass.
• Envelope -this is an amorphous structure composed of lipid, protein and carbohydrate which lies to the outside of the capsid.
• Spikes.

Is influenza RNA or DNA?