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What does fibrates do to your body?
Fibrates are cholesterol-lowering medicines. They work by decreasing your triglycerides, a type of fat in your blood. Fibrates can also increase your levels of high-density lipoprotein (HDL) cholesterol. If you have high triglycerides, taking fibrates may decrease your risk of heart disease, heart attack and stroke.
What is the difference between statins and fibrates?
Statins lower LDL-cholesterol (LDL-C), with limited effects on other lipid parameters. Fibrates improve atherogenic dyslipidemia characterized by high triglyceride and/or low HDL-C levels and elevated concentrations of small dense LDL particles, with or without high LDL-C levels.
Why does Fibrate increase LDL?
Patients with severe hypertriglyceridemia frequently have low levels of LDL cholesterol, and treatment with fibrates may raise their LDL cholesterol levels by increasing intravascular lypolysis of very low-density lipoproteins (VLDL) through lipoprotein lipase, with resultant accumulation of newly formed LDL (‘beta- …
Does fenofibrate reduce LDL?
Fenofibrate lowered LDL-C by 6% and TG by 28%, and raised HDL-C by 7%. Fenofibrate slowed the angiographic progression of coronary atherosclerosis: the progression of focal coronary atheroma was 40% less in the fenofibrate group compared with placebo, without significant effect on diffuse atheroma.
What foods contain fibrates?
Oat bran is the best-known example; 1–2 ounces a day should reduce your cholesterol by 10%–15%. Other excellent sources include beans, barley, prunes, citrus fruits, apples, Brussels sprouts, broccoli, and apricots. Psyllium, a natural grain from India, is also rich in soluble fiber.
Does Bezafibrate lower cholesterol?
What is bezafibrate? Bezafibrate is used to lower cholesterol (mainly triglycerides) levels in your blood. Bezafibrate is usually used in combination with a statin in people with high triglyceride levels or it is prescribed when statins cannot be used to lower cholesterol.
How long should you take fenofibrate?
Monitoring of cholesterol/triglyceride levels every four to eight weeks is important to establish the effectiveness of fenofibrate therapy. Your doctor should consider discontinuing therapy if you have not had an adequate response after two months of treatment.
Can you take bezafibrate long term?
Following this advice will also help you to reduce your risk of developing heart and blood vessel disease. Treatment with bezafibrate is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.