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Can you IV push cefepime?
Several antibiotics are Food and Drug Administration–approved for IV push administration, including many beta-lactams. In addition, cefepime, ceftriaxone, ertapenem, gentamicin, and tobramycin have primary literature data to support IV push administration.
Can cefepime be reconstituted with sterile water?
Intramuscular Administration: For IM administration, MAXIPIME (cefepime hydrochloride) should be constituted with one of the following diluents: Sterile Water for Injection, 0.9% Sodium Chloride, 5% Dextrose Injection, 0.5% or 1.0% Lidocaine Hydrochloride, or Sterile Bacteriostatic Water for Injection with Parabens or …
How do you administer ceftriaxone IV push?
The injection should be administered over 5 minutes, directly into the vein or via the tubing of an intravenous infusion. Ceftriaxone can be administered by intravenous infusion over at least 30 minutes (preferred route) or by slow intravenous injection over 5 minutes.
How do you administer cefepime IV?
Cefepime injection comes as a powder to be mixed with liquid, or as a premixed product, to be injected intravenously (into a vein) over a period of 30 minutes. Cefepime injection can also be given intramuscularly (into a muscle). It is usually given every 8 or 12 hours for 7 to 10 days.
Can you give antibiotics IV push?
Several antibiotics are Food and Drug Administration-approved for IV push administration, including many beta-lactams. In addition, cefepime, ceftriaxone, ertapenem, gentamicin, and tobramycin have primary literature data to support IV push administration.
How do I reconstitute cefepime IM?
For IM injection, reconstitute vial containing 500 mg or 1 g of cefepime with 1.3 or 2.4 mL, respectively, of sterile water for injection, 0.9% sodium chloride, 5% dextrose, 0.5 or 1% lidocaine hydrochloride, or bacteriostatic water for injection (with parabens or benzyl alcohol) to provide a solution containing …
Is cefepime water soluble?
Cefepime hydrochloride is a white to pale yellow powder. Cefepime hydrochloride contains the equivalent of not less than 825 mcg and not more than 911 mcg of cefepime (C19H24N6O5S2) per mg, calculated on an anhydrous basis. It is highly soluble in water.
How do you reconstitute ceftriaxone IV?
Reconstitute Rocephin powder with the appropriate diluent (see COMPATIBILITY AND STABILITY). Inject diluent into vial, shake vial thoroughly to form solution….Intravenous Administration.
| Vial Dosage Size | Amount of Diluent to be Added |
|---|---|
| 250 mg | 2.4 mL |
| 500 mg | 4.8 mL |
| 1 gm | 9.6 mL |
| 2 gm | 19.2 mL |
How do you reconstitute IV antibiotics?
Reconstitute a 1 g vial and a 2 g vial each with 10 mL of sterile water for injection • Administer each 1 g dose by slow IV push over 3 to 5 minutes. Administer each 2 g dose by slow IV push over 3 to 5 minutes. minutes. Local thrombophlebitis can occur.
How do you administer IV cefepime?
Can you reconstitute cefepime with lidocaine?
How do you dilute IV cefepime?
Reconstitution and Dilution Reconstitute ADD-Vantage vials containing 1 or 2 g of cefepime with 50 or 100 mL of 0.9% sodium chloride or 5% dextrose injection according to the manufacturer’s directions.
Is cefepime compatible with normal saline?
No interactions were found between cefepime and Normal Saline Flush.
How do you reconstitute cefepime?
Reconstitute vials containing 500 mg, 1 g, or 2 g of cefepime with 5, 10, or 10 mL, respectively, of compatible IV solution to provide solutions containing approximately 100, 100, or 160 mg/mL, respectively. Then further dilute the appropriate dose of reconstituted solution in a compatible IV solution.
How do you administer cefepime 2GM via IV push?
Administer the cefepime 2gm via IV push over 5 minutes. 18. Discard the needle and syringe in the sharps container. Author Burgener, Natasha Created Date
How is cefepime administered in the treatment of Pseudomonas infections?
Guidelines suggest cefepime with metronidazole as empiric therapy in patients with high risk or severity community-acquired, health care-associated, or biliary infections. 2 g IV every 12 hours in combination with metronidazole for 7 to 10 days. For infections caused by Pseudomonas aeruginosa, 2 g IV every 8 hours.
What is the clinical pharmacology of cefepime?
Cefepime – Clinical Pharmacology. The exposure to Cefepime following a 50 mg per kg intravenous dose in a pediatric patient is comparable to that in an adult treated with a 2 g intravenous dose. The absolute bioavailability of Cefepime after an intramuscular dose of 50 mg per kg was 82.3 (±15)% in eight patients.