What is a planar xanthoma?

What is a planar xanthoma?

  Plane (planar) xanthomas are circumscribed or diffuse, yellow / orange macules, patches, or plaques that may occur in limited anatomical areas or may be more generalized.

What is xanthoma disease?

Xanthoma is a skin condition in which certain fats build up under the surface of the skin. Xanthomas are raised, waxy-appearing, frequently yellowish-colored skin lesions. They may be associated with an underlying lipid (cholesterol/triglyceride) abnormality.

What is an associated condition of a plane xanthoma of the palmar creases?

Discussion. Xanthomas are lesions characterized by accumulations of lipid-laden macrophages. They are commonly associated with all types of hyperlipidemia. However, type III hyperlipidemia is particularly known to be associated with palmar xanthomas and has a proclivity to the development of premature atherosclerosis.

How is xanthoma treated?

There are no treatment guidelines for xanthoma disseminatum and verruciform xanthomas, but surgical treatment may be appropriate for lesions that are disfiguring or impair function. Xanthoma disseminatum has been described to respond to 2-chlorodeoxyadenosine, simvastatin, or to combination of lipid-lowering agents.

What are the different types of Hyperlipoproteinemia?

There are five types of primary hyperlipoproteinemia:

• Type 1 is an inherited condition.
• Type 2 runs in families.
• Type 3 is a recessively inherited disorder in which intermediate-density lipoproteins (IDL) accumulate in your blood.
• Type 4 is a dominantly inherited disorder.
• Type 5 runs in families.

What is xanthomas caused by?

Xanthomas are small skin blemishes that happen due to a buildup of fats under the surface of the skin. They can also develop on internal organs. The bumps themselves are not dangerous. However, they are often a symptom of other health conditions such as diabetes or high cholesterol.

Is Hyperlipoproteinemia high cholesterol?

Hyperlipidemia means your blood has too many lipids (or fats), such as cholesterol and triglycerides. One type of hyperlipidemia, hypercholesterolemia, means you have too much non-HDL cholesterol and LDL (bad) cholesterol in your blood. This condition increases fatty deposits in arteries and the risk of blockages.

What does xanthomas look like?

Symptoms of Xanthomas They might appear as single bumps or in clusters. A large group of them may occur all at once. They do not have a uniform shape and size, and their color might vary from reddish to yellowish. The bumps may be itchy or tender to the touch.

What could cause Hyperlipoproteinemia?

Causes of hyperlipoproteinemia It’s a result of a defect or mutation in lipoproteins. These changes result in problems with accumulation of lipids in your body. Secondary hyperlipoproteinemia is the result of other health conditions that lead to high levels of lipids in your body.

How is Hyperlipoproteinemia diagnosed?

A doctor can diagnose hyperlipoproteinemia with a blood test. Sometimes, family history is useful. If you have lipid deposits on your body, your doctor will also examine those. Other diagnostic tests might measure thyroid function, glucose, protein in the urine, liver function, and uric acid.

What is the causes of xanthoma?

Xanthoma is usually caused by high levels of blood lipids, or fats. This may be a symptom of an underlying medical condition, such as: hyperlipidemia, or high blood cholesterol levels. diabetes, a group of diseases that causes high blood sugar levels.