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What is a possible complication associated with succinylcholine administration?
However succinylcholine is associated with severe hyperkalaemia, arrhythmia and cardiac arrest especially in severe burn and neuromuscular disease and renal failure.
What happens when you give succinylcholine?
A depolarizing neuromuscular blocking agent, succinylcholine adheres to post-synaptic cholinergic receptors of the motor endplate, inducing continuous disruption that results in transient fasciculations or involuntary muscle contractions and subsequent skeletal muscle paralysis.
What is Quelicin used for?
Quelicin (succinylcholine chloride) Injection is a short-acting depolarizing skeletal muscle relaxant used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
How do you administer succinylcholine?
Intramuscular Use. If necessary, succinylcholine may be given intramuscularly to infants, older children, or adults when a suitable vein is inaccessible. A dose of up to 3 to 4 mg/kg may be given, but not more than 150 mg total dose should be administered by this route.
Does succinylcholine cause hypotension?
Background: Succinylcholine causes immediate and severe arterial hypotension in swine with the malignant hyperthermia phenotype. The underlying mechanisms are unknown.
Why succinylcholine is given during intubation?
Succinylcholine dose of 0.45 mg/kg provides an optimal intubation condition in ASA III & IV emergency non-prepared patients. Duration of action of succinylcholine is dose dependent; reducing the dose allows a more rapid return of spontaneous respiration and airway reflexes.
Does midazolam cause respiratory depression?
Midazolam, like other CNS depressants, may produce respiratory depression. This is especially likely to occur in patients who are receiving other CNS depressants (opioids, barbiturates) concurrently and in patients with preexisting cardiopulmonary disease.
What are contraindications of midazolam?
CONTRAINDICATIONS: Injectable midazolam is contraindicated in patients with a known hypersensitivity to the drug. Benzodiazepines are contraindicated in patients with acute narrow-angle glaucoma. Benzodiazepines may be used in patients with open-angle glaucoma only if they are receiving appropriate therapy.
How do you administer propofol?
Usual dose: 1 to 1.5 mg/kg. 40 mg IV every 10 seconds until onset of anesthesia. Usual dose: 2 to 2.5 mg/kg. 20 mg IV every 10 seconds until onset of anesthesia.
How does midazolam affect the heart?
A bolus of midazolam lowered the cardiac output by 24.1%. Arterial blood pressure, oxygen consumption, and mixed venous oxygen content fell significantly. There was a tendency for all variables subsequently to recover towards baseline values, within one hour, during a continuous infusion.
Does midazolam affect heart rate?
Conclusions: When administered in sedative doses, dexmedetomidine and, to a lesser extent, midazolam, reduces BP in a dose-dependent fashion. Dexmedetomidine also reduces HR. Midazolam does not affect BP or HR.