Table of Contents
What is cefotaxime injection used to treat?
Cefotaxime injection is used to treat certain infections caused by bacteria including pneumonia and other lower respiratory tract (lung) infections; gonorrhea (a sexually transmitted disease); meningitis (infection of the membranes that surround the brain and spinal cord) and other brain and spinal cord infections; and …
How do you dilute Claforan?
CLAFORAN Sterile 1 g or 2 g may be reconstituted in 50 mL or 100 mL of 5% Dextrose or 0.9% Sodium Chloride in the ADD-Vantage diluent container.
Is cefotaxime a penicillin?
Cefotaxime is a β-lactam antibiotic (which refers to the structural components of the drug molecule itself). As a class, β-lactams inhibit bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs).
How long can cefotaxime be used?
The duration of the treatment depends on the course of the disease. As a general rule Cefotaxime is administered for a further 3 to 4 days after improvement/regression of the symptoms. Adults and children over 12 years in general receive 1 g Cefotaxime every 12 hours.
What is the difference between ceftriaxone and cefotaxime?
Ceftriaxone and cefotaxime are similar in antibacterial spectrum and resistance to beta-lactamases, but differ markedly in serum protein binding and elimination half-life (ceftriaxone: 95% protein bound, elimination half-life of 8.8 h versus cefotaxime: 35%, 1.2 h) (1,2).
Can cefotaxime treat gonorrhea?
Cefotaxime is a third-generation cephalosporin with excellent in vitro antimicrobial activity against Neisseria gonorrhoeae, including beta-lactamase-producing strains. A single 1-g intramuscular dose is suitable for the treatment of uncomplicated gonorrhea.
Is Claforan a penicillin?
Claforan is a cephalosporin (SEF a low spor in) antibiotic. Claforan is used to treat many kinds of bacterial infections, including severe or life-threatening forms. This medicine is also used to prevent infection in people having certain types of surgery.
What is Claforan used for?
Cefotaxime is a cephalosporin (SEF a low spor in) antibiotic. Cefotaxime is used to treat many kinds of bacterial infections, including severe or life-threatening forms. Cefotaxime is also used to prevent infection in people having certain types of surgery.
Does cefotaxime cover UTI?
Abstract. According to available studies the experience with cefotaxime in the treatment of urinary tract infections (UTI) is presented. Because of its broad spectrum antibacterial activity cefotaxime is active against most of the causative organisms, including multiresistant strains (except enterococci).
What is the brand name of cefotaxime?
Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Which is stronger cefotaxime or ceftriaxone?
The two treatment groups did not differ in types of infection, infecting organisms, and severity of underlying disease. The response rate was 81% (71/88) for ceftriaxone and 80% (66/83) for cefotaxime. The power of the study to detect a 15% difference in response rate at P less than . 1 was 90%.
Which is better ceftriaxone or cefuroxime?
We conclude that ceftriaxone is superior to cefuroxime for the treatment of acute bacterial meningitis in children and that the benefits of milder hearing impairment and more rapid sterilization of the cerebrospinal fluid with ceftriaxone outweigh the problem of reversible biliary pseudolithiasis with this drug.
What is CLAFORAN used for?
Is CLAFORAN an antibiotic?
Sterile CLAFORAN (cefotaxime sodium) is a semisynthetic, broad spectrum cephalosporin antibiotic for parenteral administration.
Is Claforan an antibiotic?
Does cefotaxime cover E coli?
In contrast to their high rates of resistance to ampicillin, most E. coli infections are susceptible to cefotaxime.