What is supprelin LA used for?
Histrelin implant (Supprelin LA) is used to treat central precocious puberty (CPP; a condition causing children to enter puberty too soon, resulting in faster than normal bone growth and development of sexual characteristics) in girls usually between 2 and 8 years of age and in boys usually between 2 and 9 years of age …
How is supprelin La administered?
SUPPRELIN LA is placed under the skin of the inside of the upper arm. The doctor will temporarily numb the arm of your child, make a small cut, and then place SUPPRELIN LA under the skin. The cut may be closed with stitches or surgical strips and covered with a pressure bandage.
Is supprelin the same as Lupron?
by Drugs.com Supprelin LA is not the same as Lupron Depot-Ped, because Supprelin LA contains the active drug histrelin acetate, while Lupron Depot-Ped contains the active drug leuprolide acetate.
What is GnRH used for?
Gonadotropin releasing hormone agonists (GnRH) are a type of medication that suppresses ovulation by stopping the production of estrogen and progesterone. In order for this axis to function properly and result in ovulation, GnRH has to be released in a pulsatile fashion.
What do hormone blockers do?
Puberty blockers, also called hormone blockers, help delay unwanted physical changes that don’t match someone’s gender identity. Delaying these changes can be an important step in a young person’s transition. It can also give your child more time to explore their options before deciding whether or how to transition.
Who manufactures supprelin LA?
Indevus Announces FDA Approval of SUPPRELIN(R)-LA. LEXINGTON, Mass., May 3 /PRNewswire-FirstCall/ — Indevus Pharmaceuticals, Inc. (Nasdaq: IDEV) today announced that SUPPRELIN(R)-LA (histrelin acetate subcutaneous implant) 50mg has been approved by the U.S. Food and Drug Administration (FDA).
How soon after Lupron injection do side effects start?
Rarely, a very serious problem with your pituitary gland (pituitary apoplexy) may occur, usually in the first hour to 2 weeks after the first injection.
What is a blocker implant?
The recommended treatment is a product commonly known as a hormone blocker. Implanted beneath the skin in her arm, it releases a small dose of a drug each day that increases the body’s production of some hormones while decreasing others. The result is the child’s progression toward adulthood slows.
How long does it take GnRH to work?
You should notice an improvement in your symptoms within 4–8 weeks of beginning treatment, but some women will experience a temporary worsening of symptoms in the first 2 weeks.
How long can you be on hormone blockers?
Injectable blockers (such as Lupron) can last one, three or six months. Patients can continue getting injections until they decide what to do next. Implants (such Supprelin), which are placed just under the skin in the arm, can last 12 to 24 months before they need to be replaced.
When should you start taking hormone blockers?
You may need to wait until you are 16 years old to begin hormone treatment, but you may be able to take puberty blockers in the meantime. What are the risks of puberty blockers and hormone treatment? Puberty blockers may: Slow your physical growth and affect your height.
Is supprelin FDA approved?
(Nasdaq: IDEV) today announced that SUPPRELIN(R)-LA (histrelin acetate subcutaneous implant) 50mg has been approved by the U.S. Food and Drug Administration (FDA). SUPPRELIN-LA is indicated for the treatment of central precocious puberty (CPP), the premature onset of puberty in children.
Is Lupron considered a chemotherapy drug?
Lupron is an antineoplastic (anti-cancer) drug that belongs to a class called gonadotropin-releasing hormone (GnRH) agonists. It is also known as androgen deprivation therapy (ADT) or antiandrogen. Lupron is a type of chemotherapy that prevents cancer cells from multiplying and restricts their growth.
Does Lupron make you sleepy?
SIDE EFFECTS: Mild burning/pain/bruising at the injection site, hot flashes (flushing), increased sweating, night sweats, tiredness, headache, upset stomach, breast changes, acne, joint/muscle aches, trouble sleeping, reduced sexual interest, vaginal discomfort/dryness, vaginal bleeding, swelling of the ankles/feet.