What is a Smouldering infection?
Smoldering multiple myeloma (SMM) is a condition that affects plasma cells in the bone marrow. These are a type of white blood cell that help keep the body safe from infection. SMM is a subdivision of multiple myeloma, which is a type of blood cancer.
What does smoldering cancer mean?
Smoldering myeloma is a slow-growing type of multiple myeloma, a form of cancer in which abnormal plasma cells (purple) make too much of a single type of antibody.
How serious is smoldering myeloma?
Patients with intermediate-risk disease have a 50% chance of needing treatment, and patients with high-risk disease have a 75% to 80% chance of needing treatment. “Even patients with low-risk smoldering myeloma are at risk of progression,” Manasanch says.
What is the difference between smoldering myeloma and multiple myeloma?
Smoldering myeloma is a precursor stage of multiple myeloma. Historically, smoldering myeloma patients have not been put on active treatment because many of them only have a 10% risk per year for the first 5 years of progressing to active myeloma (with a cumulative 50% risk).
How long can I live with smoldering myeloma?
Multiple myeloma is a cancer of the bone marrow. Bone marrow is the spongy tissue inside the long bones….Multiple Myeloma Survival Rates.
| A revised international staging system | Median survival |
|---|---|
| Stage I | 62 months (5 years, 2 months) |
| Stage II | 42 months (3.5 years) |
| Stage III | 29 months (2 years, 5 months) |
How do you know if you have smoldering myeloma?
Your doctor may notice signs of smoldering multiple myeloma on lab tests you take for any reason. Your blood or urine test may show high levels of M protein. Or you may have a blood test that shows high levels of plasma cells.
How long can a person have smoldering myeloma?
Among patients with progression of smoldering multiple myeloma, 97% had progression to active multiple myeloma. Rates of death owing to other diseases, including cardiovascular and cerebrovascular disease and non–plasma-cell cancers, were 18% at 5 years, 26% at 10 years, 30% at 15 years, and 35% at 20 years.
How long can you live with smoldering myeloma?
The overall rate of survival was 60% at 5 years, 34% at 10 years, and 20% at 15 years (median, 6.3).
How long can you live with myeloma?
Survival statistics for myeloma more than 50 out of every 100 (more than 50%) will survive their myeloma for 5 years or more after diagnosis. around 30 out of every 100 (around 30%) will survive their myeloma for 10 years or more after they are diagnosed.