What is the normal range for HBV DNA viral load?
HBV: Hepatitis B virus. # Normal values: ALT: Males: 10-40 U/L; Females: 7 – 35 U/L; AST: Males: 15 – 40 U/L; Females: 13 – 35 U/L. HBeAg-positive patients had significantly higher ALT levels (mean 170.3 ± 391 IU/L) compared to HBeAg-negative patients (mean 53.9 ± 169.4 IU/L), p < 0.0001 (Table 2).
How do you interpret Hep B viral load?
Similarly, in a person with an HBeAg-negative chronic hepatitis B, an HBV viral load of greater than 2,000 IU/mL indicates that the virus is active and has the potential to cause damage to the liver. Generally speaking, if the HBV viral load is above these numbers, treatment is considered necessary.
What is a high viral load for hep B?
A viral load of > 10 000 copies/mL (2000 IU/mL) is a strong risk predictor of HCC, independent of HBeAg status, ALT level and liver cirrhosis[10,21,22].
How do the doctors interpret the results of the HBV DNA test?
Positive HBsAg indicates current infection, positive anti-HBs indicates immunity (through vaccination or past infection), and positive anti-HBc indicates past or current infection (this test may occasionally give a false-positive result).
What is HBV viral DNA?
The hepatitis B virus (HBV) is a small DNA virus with unusual features similar to retroviruses. 1,2. It is a prototype virus of the Hepadnaviridae family. Related viruses are found in woodchucks, ground squirrels, tree squirrels, Peking ducks, and herons.
What is HBV DNA quantitative test?
A quantitative result expressed in IU/mL and log IU/mL indicates the degree of active HBV viral replication in the patient. Monitoring HBV DNA levels over time is important for assessing disease progression or monitoring a patient’s response to anti-HBV therapy.
What is HBV DNA log?
How do you read viral load results?
Viral load results are reported as copies of HIV in one milliliter of blood. The lower the number, the less virus there is in your blood. Numbers can range from about one million copies to as few as 50 copies. If you have fewer than 50 copies, your health care provider may tell you that your results are “undetectable.”
What is the meaning of HBV DNA?
Serum levels of hepatitis B virus (HBV) DNA are an important predictor of the risk of hepatocellular carcinoma (HCC) in patients with chronic HBV infection. However, little is known about whether high levels of hepatitis B surface antigen (HBsAg) increase the risk for HCC.
What do viral load numbers mean?
Viral load refers to the amount of virus in an infected person’s blood. This is expressed as the number of viral particles in each milliliter of blood. Higher viral load can have different implications for different viruses but typically means the infection is progressing.
What is a good viral load number?
CD4 count vs. viral load
| How serious is this? | CD4 level | Viral load |
|---|---|---|
| Monitoring is essential, but a doctor may consider levels stable. | 300–500 cells/mm3 | less than 200 copies/mL |
| Acceptable levels. | 500–1,500 cells/mm3 | less than 20–75 copies/mL |
Is hepatitis B a highly contagious disease?
Hepatitis B is highly contagious. It spreads through contact with infected blood and certain other bodily fluids. Although the virus can be found in saliva, it’s not spread through sharing utensils or kissing. It also doesn’t spread through sneezing, coughing, or breastfeeding.
Is hepatitis B treatable and curable?
When hepatitis B infection becomes chronic, it is not curable. People with chronic hepatitis B typically need lifelong treatment. The first step in getting the right treatment for chronic hepatitis B is seeing a liver specialistor hepatologist. Other doctors who treat hepatitis B include infectious disease doctors, gastroenterologists, and internists.
Is hepatitis B the same as herpes simplex virus?
The answer is no! Herpes viruses are their own family and include genital herpes, the virus that causes cankasores and chicken pox. Hepatitis A B and C are all different from each other and belong to different virus families.
Can hepatitis B detected in normal blood test?
Tests that can help diagnose hepatitis B or its complications are: Blood tests. Blood tests can detect signs of the hepatitis B virus in your body and tell your doctor whether it’s acute or chronic. A simple blood test can also determine if you’re immune to the condition.