What does Alpha TTP do?

What does Alpha TTP do?

Alpha-tocopherol transfer protein (α-TTP) is a liver cytosolic transport protein that faciliates α-tocopherol (α-T) transfer into liver secreted plasma lipoproteins. Genetic defects in α-TTP, like dietary vitamin E deficiency, are associated with infertility, muscular weakness and neurological disorders.

What is the function of vitamin E?

Vitamin E is a fat-soluble vitamin with several forms, but alpha-tocopherol is the only one used by the human body. Its main role is to act as an antioxidant, scavenging loose electrons—so-called “free radicals”—that can damage cells.

What causes vitamin e deficiency?

Vitamin E deficiency is extremely rare in humans as it is unlikely caused by a diet consisting of low vitamin E. Rather, it tends to be caused by irregularities in dietary fat absorption or metabolism. Vitamin E is a lipid-soluble nutrient.

Is tocopherol a protein?

α-Tocopherol transfer protein (αTTP), which was recently identified as a product of the causative gene for familial isolated vitamin E deficiency, is a cytosolic liver protein and plays an important role in the efficient recycling of plasma vitamin E.

Is tocopherol a chemical?

Tocopherols (/toʊˈkɒfəˌrɒl/; TCP) are a class of organic chemical compounds (more precisely, various methylated phenols), many of which have vitamin E activity.

Is alpha-tocopherol vitamin E?

It also helps prevent cell damage caused by free radicals (highly reactive chemicals). Alpha-tocopherol is being studied in the prevention and treatment of some types of cancer. It is a type of antioxidant. Also called vitamin E.

Where is alpha-tocopherol found?

The most biologically active form for mammals is α-tocopherol, which is the dominant form of vitamin E found in blood and tissues. The estimated average requirement of α-tocopherol for people is 12 mg d−1, but dietary intakes and plasma levels of α-tocopherol show considerable inter individual variation.

What is another name for alpha-tocopherol?

vitamin E
Alpha-tocopherol is being studied in the prevention and treatment of some types of cancer. It is a type of antioxidant. Also called vitamin E.

What is alpha-tocopherol made from?

Tocopherols are found in almost all plant seeds, the best sources of alpha-tocopherol include plant seeds such as almonds, sunflower seeds and hazelnuts. Olive and canola oil are also good sources, as are tomato, avocado and spinach….Sources of tocopherols.