When should daptomycin Cubicin be discontinued?
Daptomycin should be discontinued in patients with symptoms of muscle pain or weakness whose CPK levels exceed 1000 U/L (~ 5x ULN), or in patients without symptoms whose CPK exceeds 10x ULN.
Is daptomycin the same as vancomycin?
Daptomycin, a lipopeptide antibiotic, is approved by the US Food and Drug Administration for the treatment of S. aureus bacteremia and is considered a reasonable alternative to vancomycin. The efficacy of daptomycin has been demonstrated in an open-label randomized clinical trial by Fowler et al.
How do you administer a Cubicin?
CUBICIN should be administered intravenously either by injection over a two (2) minute period or by infusion over a thirty (30) minute period. CUBICIN 4 mg/kg should be administered intravenously in 0.9% sodium chloride injection once every 24 hours for 7 to 14 days.
How expensive is daptomycin?
Daptomycin cost is normally $1,490.36 for 3, 500MG Solution Reconstituted at full price. Daptomycin is administered by healthcare professionals.
Is daptomycin hard on the kidneys?
This medicine may cause serious skin reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS), which can damage organs, including the liver, kidney, or heart.
What does daptomycin cost?
(Generic Cubicin) Daptomycin is administered by a healthcare professional as a slow injection or as an intravenous infusion. Daptomycin cost is normally $1,490.36 for 3, 500MG Solution Reconstituted at full price. Daptomycin is administered by healthcare professionals.
Who manufactures Cubicin?
Daptomycin
| Product grades | Non-sterile |
|---|---|
| Manufacturing site | Xellia Pharmaceuticals Ltd., Budapest, Hungary |
| Release site | Xellia Pharmaceuticals Ltd., Budapest, Hungary |
| Site registered | EU GMP issued by Hungarian National Institute of Pharmacy US FDA |
| Regulatory documentation | US Drug Master File (DMF) EU Drug Master File (DMF) |
What is the generic name for Cubicin?
Daptomycin (Cubicin) is an injectable antibiotic used to treat serious bacterial infections of the skin and underlying tissues and infections that have entered the bloodstream. Daptomycin (Cubicin) is usually used for complicated and serious infections since it is a strong antibiotic.
How much is a vial of daptomycin?
The cost for daptomycin intravenous powder for injection 500 mg is around $29 for a supply of 1 powder for injection, depending on the pharmacy you visit….Intravenous Powder For Injection.
| Quantity | Per unit | Price |
|---|---|---|
| 1 | $29.08 – $176.33 | $29.08 – $176.33 |
| 10 each | $167.78 | $1,677.76 |
Is Cubicin same as daptomycin?
How much does Cubicin cost?
Cubicin Prices. This Cubicin price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies. The cost for Cubicin intravenous powder for injection 500 mg is around $474 for a supply of 1 powder for injection, depending on the pharmacy you visit.
Is Cubicin being discontinued?
Discontinuation: The sale of CUBICIN® (daptomycin for injection) 500 mg / 10 mL single-dose vial, NDC 67919-011-01, has been discontinued. CUBICIN® RF (daptomycin for injection) 500 mg / 10 mL single-dose vial, NDC 67919-012-01 remains available.
Is Cubicin daptomycin still available?
CUBICIN® RF (daptomycin for injection) 500 mg / 10 mL single-dose vial, NDC 67919-012-01 remains available. Voluntary Recall: One lot of CUBICIN® (daptomycin for injection) 500 mg for intravenous use, Lot 934778, Exp. June 2022, is being recalled by Merck effective October 19, 2021.
What are the side effects of Cubicin?
Anaphylaxis/hypersensitivity reactions, which may be life-threatening, have been reported with CUBICIN use. If an allergic reaction occurs, discontinue CUBICIN or CUBICIN RF and treat appropriately. Myopathy and rhabdomyolysis have been reported with CUBICIN use.