Table of Contents
Where does sterigmatocystin come from?
Sterigmatocystin (STC) is a carcinogenic and mutagenic mycotoxin produced by fungi of many Aspergillus species. As a precursor of the aflatoxins, STC is a risk factor of liver cancer.
What is Sterigmatocystin used for?
Sterigmatocystin is a carcinogenic compound that induces tumors in several animal species. Sterigmatocystin can be found in different food such as spices, grains, bread, beer, and cheeses. Different analytical methods are used to determine sterigmatocystin in food.
Can mold affect your kidneys?
Mold exposure is exposure to a chemical (mycotoxin) which can affect heart, lungs, liver, kidneys, immune system, brain, and almost every cell in the body.
What foods have mycotoxins?
Mycotoxins appear in almost all kinds of animal feed and products such as wheat bran, noug cake, pea hulls, maize grain, milk and meat, and also human food such as cereal, fruit and vegetables, spice, etc. [5]. Consuming these foods creates serious health risks in human and all animal species.
Can black mold cause kidney problems?
Beside the Chronic Fatigue Syndrome (CFS), mycotoxins’ exposure can have acute complications like kidney or hepatic failure. It can also have teratogenic effects on the fetus in pregnant women. Prolonged exposure to mycotoxins (for many years) also increases the risk of some types of cancer like lung carcinoma.
Is zearalenone harmful to humans?
This property of zearalenone determines its ability to bind to estrogen receptors of cell and its bioaccumulation. This leads to disorders of the hormonal balance of the body, which in consequence may lead to numerous diseases of reproductive system such as prostate, ovarian, cervical or breast cancers.
What are the types of aflatoxin?
There are more than 20 known aflatoxins, but the four main ones are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1), and aflatoxin G2 (AFG2; Inan et al., 2007), while aflatoxin M1 (AFM1) and M2 (AFM2) are the hydroxylated metabolites of AFB1 and AFB2 (Giray et al., 2007; Hussain and Anwar, 2008).
How do I get rid of mycotoxins?
Mycotoxins are found in these bile acids, so guggulsterone can effectively remove these mycotoxins through its elimination of the bild acids. Cholestyramine is a commonly prescribed medication for mold exposure, particularly for ochratoxin mycotoxins.
What are symptoms of black mold making you sick?
Symptoms of Black Mold Exposure
- Coughing.
- Postnasal drip.
- Sneezing.
- Dry, scaly skin.
- Itchy eyes, nose, or throat.
- Nasal congestion.
What is sterigmatocystin?
The toxin is naturally found in some cheeses. Sterigmatocystin is a toxic metabolite structurally closely related to the aflatoxins, and consists of a xanthone nucleus attached to a bifuran structure. Sterigmatocystin is mainly produced by the fungi Aspergillus nidulans and A. versicolor.
Is sterigmatocystin aflatoxin?
Sterigmatocystin is produced by several species of Aspergillus, Penicillium luteum, and a Bipolaris species. Chemically, sterigmatocystin resembles the aflatoxins and is thought to be a precursor in the biosynthesis of aflatoxin.
Is sterigmatocystin a hepatotoxic?
The acute toxicity, carcinogenicity, and metabolism of sterigmatocystin has been compared with those for aflatoxin and several other hepatotoxic mycotoxins.
How do you make sterigmatocystin toxic?
Sterigmatocystin reacts with a hot solution of potassium hydroxide and ethanol and is easily methylated by methyl iodide. Treatment with ethanol in acid produces dihydroethoxysterigmatocystin. The toxic effects of sterigmatocystin are much the same as those of aflatoxin B1.