Table of Contents
Can you add electrolytes to CLINIMIX?
For 2-in-1 therapy, CLINIMIX (amino acids in dextrose) Injections and CLINIMIX E (amino acids with electrolytes in dextrose with calcium) Injections may be admixed in the pharmacy and lipids may be piggybacked at the appropriate time during infusion.
How is CLINIMIX administered?
Clinimix E is for intravenous infusion only into a central or peripheral vein. The choice of a central or peripheral venous route should depend on the osmolarity of the final infusate. Solutions with osmolarity of 900 mOsm/L or greater must be infused through a central catheter [see Warnings and Precautions (5.7)].
Does CLINIMIX need a central line?
CLINIMIX and CLINIMIX E solutions containing more than 5% dextrose have an osmolarity of ≥ 900 mOsm/L and must be infused through a central catheter.
Does CLINIMIX require a filter?
Use a 0.22 micron filter for administration of CLINIMIX E. If a lipid is also administered, use a 1.2 micron filter. If lipid emulsion is added, do not use administration sets and lines that contain di-2-ethylhexyl phthalate (DEHP).
How do you mix CLINIMIX?
The top of the bag (hanger end) should be nearest you with the ports pointing away from you. Grasp the bag on each side of the top of the bag. Using some pressure, slowly roll the bag to open the seal between the chambers (Figure 3). Be sure the contents of both chambers are mixed together after breaking the peel seal.
How long can a CLINIMIX bag hang?
Any storage should be under refrigeration and limited to less than 24 hours. Hang bag. Remove twist-off protector from Administration Port (Figure 7).
Is CLINIMIX refrigerated?
Any storage should be under refrigeration and limited to less than 24 hours. Hang bag.
What filter do you use for TPN?
1.2-micron filter
The use of an in-line, 1.2-micron filter is recommended for the infusion of total parenteral nutrition (TPN), also known as 3-in-1 or all-in-one [AIO], and intravenous fat emulsions (IVFE) infused alone through a separate IV line.
Why do we use filter for TPN?
In-line intravenous filters serve a critical purpose in reducing exposure to particulate matter during parenteral nutrition (PN) therapy. Particles greater than 2 microns, which are retained by 1.2 micron filters, appear to pose the most serious risk for adverse consequences.
Who makes CLINIMIX?
Baxter
Baxter Announces U.S. FDA Approval of Clinimix and Clinimix E with Higher Protein for Patients Requiring Parenteral Nutrition | Baxter.
Does TPN need a filter?
TPN requires special IV tubing with a filter. Generally, new TPN tubing is required every 24 hours to prevent catheter-related bacteremia.
Can a 0.2 micron filter be used for TPN?
Current Recommendations for Parenteral Nutrition Filtration The 2021 INS standards recommend a 0.2 micron filter for lipid-free PN and a 1.2 micron filter for lipid-containing PN.
What size filter is used for TPN?
What does a 0.22-micron filter remove?
The 0.22-micron filter is one of the smallest used in patient care, and removes bacteria. There are not currently filters that remove viruses.
How much does Clinimix cost?
The cost for Clinimix E Sulfite Free intravenous solution (Amino Acids 4.25% with 10% Dextrose and Electrolytes (Clinimix E Sulfite-Free)) is around $310 for a supply of 6000 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
How long can a Clinimix bag hang?
What are the different port configurations of clinimix?
CLINIMIX is available in a three port container configuration and a two port container configuration. Three Port Container: the ports consist of one medication port, one additive port and one outlet port. Additives can be introduced to the container through the medication port and lipids through the additive port on the three port container.
What size filter do you use for clinimix E?
For central or peripheral vein infusion: Clinimix E 2.75/5 and 4.25/5 The solution should be inspected for precipitates before admixing, after admixing, and again before administration. Use a 0.22 micron filter for administration of CLINIMIX E.
Which clinimix solution is used for Central or peripheral vein infusion?
For central or peripheral vein infusion: Clinimix E 2.75/5 and 4.25/5 The solution should be inspected for precipitates before admixing, after admixing, and again before administration.
Is clinimix owned by Baxter?
Baxter, Clinimix and Clinimix E are trademarks of Baxter International Inc. Please see Indications and Important Risk Information on inside page Please see accompanying Package Inserts for full Prescribing Information