Table of Contents
Does trisomy 21 cause sterility?
Affected individuals rarely reproduce. About 15-30% of females with trisomy 21 are fertile and have up to a 50% risk of having child also affected with trisomy 21. Infertility in males has been attributed to defective spermatogenesis, but ignorance of the sexual act may be one of the contributing factors.
Do people with Down syndrome have low testosterone?
The Down’s syndrome group had significantly higher FSH, LH, and prolactin levels (P < 0.05 for each), significantly lower total testosterone (P < 0.05), and no difference in the estradiol level compared with the control group [Table 3]. Down’s syndrome is a relatively common chromosomal disorder.
What is the major characteristic of the most common chromosomal abnormality called trisomy 21?
The most common structural abnormalities in trisomy 21 are increased nuchal translucency, cardiac defects, and duodenal atresia.
What are some development delays associated with trisomy 21?
Down syndrome is a chromosome disorder caused by an extra chromosome 21 that results in intellectual disability and physical abnormalities. Down syndrome is caused by an extra chromosome 21. Children with Down syndrome have delayed physical and mental development, specific head and facial features, and are often short.
Can a woman with Down syndrome reproduce?
Yes. A woman with Down’s syndrome can have children. If her partner does not have Down’s syndrome, the theoretical chance of the child having Down’s syndrome is 50%. There have been only a few reports of men with Down’s syndrome fathering children.
What are the characteristics of an individual with trisomy 21?
Down syndrome (trisomy 21) is a genetic disorder. It includes certain birth defects, learning problems, and facial features. A child with Down syndrome also may have heart defects and problems with vision and hearing.
What are the clinical characteristics consistent with a diagnosis of trisomy 21?
On physical examination, patients with trisomy 21 have characteristic craniofacial findings, such as the following: Flat occiput and a flattened facial appearance. Small brachycephalic head. Epicanthal folds.
What medical conditions are associated with Down syndrome?
What conditions or disorders are commonly associated with Down syndrome?
- Heart defects.
- Vision problems.
- Hearing loss.
- Infections.
- Hypothyroidism.
- Blood disorders.
- Hypotonia (poor muscle tone).
- Problems with the upper part of the spine.
What is the difference between trisomy 21 and Down syndrome?
A medical term for having an extra copy of a chromosome is ‘trisomy. ‘ Down syndrome is also referred to as Trisomy 21. This extra copy changes how the baby’s body and brain develop, which can cause both mental and physical challenges for the baby.