Can CPPD cause erosions?
Note the indentation of the radiocarpal joint. Large subchondral cysts (ie, geodes; see the image below) are also rarely noted in CPPD. The pseudorheumatoid variety of CPPD is an erosive disease. Another variety of CPPD is described as a destructive peripheral arthritis associated with bony fragmentation.
What is CPPD on xray?
Calcium pyrophosphate dihydrate disease (CPPD), also known as pyrophosphate arthropathy or pseudogout, is defined by the co-occurrence of arthritis with evidence of CPPD deposition within the articular cartilage.
How is pseudogout diagnosed?
Lab tests. Blood tests can check for problems with your thyroid and parathyroid glands, as well as for a variety of mineral imbalances that have been linked to pseudogout. Your doctor may withdraw a sample of the fluid from your affected joint with a needle to test for the presence of crystals.
Does pseudogout show on xray?
X-rays. The calcium pyrophosphate crystals that cause pseudogout can calcify cartilage. The resulting calcifications, which doctors call chondrocalcinosis, show up on x-rays. X-rays can also show overall joint damage.
Is pseudogout erosive?
PsA can lead to destructive bone loss, and 67 % of PsA patients exhibit signs of erosive bone disease . Pseudogout is an acute manifestation of chondrocalcinosis (CC); this latter is characterised by the deposition of calcium pyrophosphate dehydrate (CPP) crystals and calcification in X-rays .
What are negatively birefringent crystals?
Uric acid crystals are often intra-cellular and appear needle-shaped and yellow (negatively birefringent) while CPPD crystals appear rhomboid shaped and blue (weakly positively birefringent).
Can gout crystals be seen on xray?
Dual-energy CT (DECT) and ultrasonography have been shown to accurately confirm the presence and extent of urate crystals. Plain film radiography may be used to evaluate gout; however, radiographic imaging findings generally do not appear until after at least 1 year of uncontrolled disease.
What are the signs and symptoms of CPPD crystal arthritis (pseudogout)?
Acute CPPD crystal arthritis (pseudogout) presents with severe acute or subacute pain, swelling, erythema, and warmth, of one or more joints and is usually self-limited. The presentation classically resembles an acute gout attack. Unlike gout, it most commonly involves the knee and the upper joints (shoulder, elbow, wrist).
What joints are affected by CPPD?
In addition, CPPD arthritis characteristically affects joints that are not affected by primary OA including metacarpophalangeal, wrist, elbow, glenohumeral and patello-femoral joints. When a radiograph report describes osteoarthritis in those joints, CPPD arthritis must be suspected.
What is calc pyrophosphate deposition disease (CPPD)?
Calcium pyrophosphate deposition disease (CPPD) is a type of crystal arthropathy which affects middle-aged and old populations. Clinical manifestation of this deposition disease rages from pseudogout syndrome to asymptomatic joint disease. The radiographic hallmark of CPPD is the presence of chondrocalcinosis and secondary osteoarthritic changes.
What is the pathophysiology of chronic CPPD arthritis?
Chronic CPPD crystal inflammatory arthritis presents with chronic, intermittent painful swelling in the peripheral joints of upper and lower extremities. Pathology