Table of Contents
Does famotidine cause bone loss?
However, the long-term, daily use of aluminum-containing antacids or proton pump inhibitors (PPI) may affect how your body absorbs calcium. These medicines also appear to increase the risk of fractures. To lessen the harm to the bones from antacids: Consider an H2-blocker such as famotidine (Pepcid) instead of a PPI.
Does Nexium cause bone loss?
Early studies of proton pump inhibitors (“PPI”) such as Nexium and Prevacid showed that the drugs interfere with the body’s ability to absorb calcium, thereby speeding up bone loss and leading to an increased number of fractures.
Why is osteoporosis a risk when taking omeprazole?
The most widely assumed mechanism is that long-term PPI use leads to decreased intestinal absorption of calcium resulting in negative calcium balance, increased osteoporosis, development of secondary hyperparathyroidism, increased bone loss and increased fractures [7,16,17,46-48,51,54, 57].
Can omeprazole cause high alkaline phosphatase?
The study showed that after eight weeks of therapy with omeprazole, the PTH level had increased by 28% in relation to the baseline among these patients, accompanied by increases in osteocalcin, alkaline phosphatase and tartrate-resistant acid phosphatase, which are markers for bone formation.
Does omeprazole lower ALP?
Urinary excretion of hydroxyproline and calcium decreased after omeprazole treatment in the study group. Serum intact PTH, alkaline phosphatase, osteocalcin, and tartrate-resistant acid phosphatase (TRAP) increased in this group.
Which vitamin is best for bones?
vitamin D
You need sufficient calcium to keep your bones healthy and vitamin D to help your body absorb calcium.
Does famotidine affect the heart?
Famotidine did not affect heart rate, blood pressure, left ventricular pressure (LVP), max.
Does famotidine effect heart?
According to the research, the same type of chemical reaction that allows stomach acid to cause heartburn and create ulcers also appears to damage and weaken diseased hearts. Blocking this process with the drug famotidine (Pepcid) may help to slow the progression of chronic heart failure (CHF).