Table of Contents
Is paclitaxel a radiosensitizer?
Abstract. Paclitaxel is efficacious against many human cancers. Because it blocks cells at the radiosensitive G2-M interface, paclitaxel has been investigated as a radiosensitiser.
Is doxorubicin a radiosensitizer?
Colony-forming assays demonstrated that composite doxorubicin-loaded micelles are radiosensitive, as shown by significantly reduced survival of cells treated by radiation + composite micelles compared with those treated with radiation + free doxorubicin or radiation alone.
Is cetuximab a radiosensitizer?
It is known that cetuximab (an epidermal growth factor receptor [EGFr] inhibitor) is a radiosensitizer.
Is chemotherapy a radiosensitizer?
Abstract. The combination of low-dose chemotherapy and thoracic radiotherapy is one of the treatments proposed in an attempt to improve the prognosis of locally advanced non-small cell lung cancer. Chemotherapeutic drugs administered at subtoxic doses act by means of a radiosensitization mechanism.
What is the role of nimorazole in the treatment of supraglottic cancer?
Nimorazole significantly improves the effect of radiotherapeutic management of supraglottic and pharynx tumors and can be given without major side-effects. A randomized double-blind phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma.
Why is misonidazole a more efficient radiosensitizer?
Misonidazole, a 2-nitroimidazole, was developed as a more efficient radiosensitizer because of its known increased electron affinity.
What is the function of nitroimidazole?
Nitroimidazoles are effective bactericidal agents against anaerobes and protozoa. They are converted into metabolites that impede intracellular bacterial DNA synthesis. The main representative of the nitroimidazoles is metronidazole.
What is the best nitroimidazole for bacterial vaginosis?
The main representative of the nitroimidazoles is metronidazole. Metronidazole is now being recommended by some investigators for the treatment of bacterial vaginosis in pregnancies at high risk for preterm delivery, as a strategy to decrease this risk (review by Joesoef 1999 ).