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Does benzalkonium chloride cause rebound congestion?
We have shown that daily use of benzalkonium chloride in oxymetazoline nasal spray for 30 days induces a more pronounced rebound swelling in healthy volunteers than does oxymetazoline nasal spray used alone for 30 days, indicating that benzalkonium chloride plays an important role in the development of RM.
Does Flonase have benzalkonium chloride?
Both Flonase and Nasacort contain benzalkonium chloride (BKC), another preservative that can dry out the nose.
Is benzalkonium chloride a steroid?
Abstract. Benzalkonium chloride (BAC) is a bactericidal preservative excipient commonly found in steroid nasal sprays used to treat allergic rhinitis and nasal polyposis.
What’s better than Flonase?
Some of the most common over-the-counter (OTC) nasal sprays include Flonase (fluticasone propionate), Nasacort (triamcinolone), and Afrin (oxymetazoline). Experts usually recommend steroid nasal sprays as go-to options for allergies because they are highly effective in lessening nasal symptoms.
Can too much nasal spray be harmful?
Overuse of nasal sprays can also lead to other side effects, including headache, coughing, nasal passage swelling (inflammation), increased risk of sinus infection, and, rarely, tears in the nostril membranes. Don’t let that scare you from getting the relief you need.
Is benzalkonium chloride safe to breathe?
Benzalkonium chloride (BAC) is a widely used disinfectant/preservative, and respiratory exposure to this compound has been reported to be highly toxic.
Is it OK to use a nasal spray everyday?
To prevent rebound congestion, use over-the-counter decongestant nasal sprays for no more than three days in a row, with as few doses as possible each day. Prescription nasal sprays containing steroids don’t cause this rebound effect, so they can be used on a daily basis for years.
Is benzalkonium chloride safe for asthmatics?
Conclusions. This study suggests that the available multi-dose nebulized solution is generally safe. However, significant bronchoconstriction can occur at a relatively low BAC dose in asthmatics with severe airway responsiveness.
What are the adverse effects of benzalkonium chloride on the nasal mucosa?
Adverse effects of benzalkonium chloride on the nasal mucosa: allergic rhinitis and rhinitis medicamentosa Prolonged, repeated use of nasal decongestants for symptomatic relief of allergic rhinitis often results in rhinitis medicamentosa (RM), a condition involving “rebound swelling” and additional congestion.
What are the precautions for benzalkonium chloride?
Read all information given to you. Follow all instructions closely. Do not take benzalkonium chloride by mouth. Use on your skin only. Keep out of your mouth, nose, ears, and eyes (may burn). Wash your hands before and after use. Do not wash your hands after use if putting this on your hand.
Can Decongestant nasal sprays cause allergic rhinitis?
Most decongestant sprays contain the preservative benzalkonium chloride (BKC), which causes toxic reactions in the nose, eyes, ears, and lungs, and may exacerbate the symptoms of allergic rhinitis. Recent studies demonstrate the effects of nasal sprays containing BKC or the decongestant oxymetazoline (OXY) in the development of RM.
Can oxymetazoline nasal spray be used without benzalkonium chloride?
Ten of the subjects had been treated with oxymetazoline nasal spray without benzalkonium chloride and 10 of them had been treated with oxymetazoline nasal spray with benzalkonium chloride.