Table of Contents
What is sulpiride used to treat?
Sulpiride, an antipsychotic, is prescribed to relieve the symptoms of schizophrenia. Schizophrenia is a mental health problem which affects your thoughts, feelings or behaviours.
What are substituted benzamides?
Abstract. The class of substituted benzamides includes compounds able to modulate dopaminergic neurons selectively and specifically. The first synthetic substituted benzamide was sulpiride, which has been replaced in the clinic by the more modern amisulpride.
How does sulpiride make you feel?
Sulpiride should help you feel calm and relaxed. It could take some time for sulpiride to have its full effect. This effect should reduce your behaviour problem. For example, it may… • help you control your temper • help you stop hurting yourself • help you stop breaking things.
Which benzamide is used as antiemetic?
Metoclopramide. Metoclopramide is a benzamide derivative of procaine that was developed in 1964 to equal the antiemetic properties of phenothiazines.
What is the mechanism of action of benzamides?
The proposed mechanism of action of substituted benzamides implies a selective modulation of the dopaminergic system in the mesocorticolimbic area, important for cognitive processing of internal and external cues, related to survival.
Is domperidone a benzamide?
Any of a class of drugs, including domperidone, metoclopramide, and trimethobenzamide, that block dopamine and serotonin receptors and stimulate acetylcholine receptors in smooth muscle. They are principally used to treat nausea and vomiting.
What is a butyrophenone used for?
Compounds containing phenyl-1-butanone. An antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium. A butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting.
What is another name for domperidone?
Domperidone comes as tablets or as a liquid that you swallow. It is available on prescription only. It is also known by the brand name Motilium.
Can paracetamol help nausea?
Does paracetamol help with nausea? “Paracetamol doesn’t specifically help with nausea – it’s used to treat aches, pains and a high temperature. It can be bought from a pharmacy combined with anti-sickness medicines, and it’s an ingredient in lots of cold and flu medicines.
Is domperidone a butyrophenone?
Chemistry. Domperidone is a benzimidazole derivative and is structurally related to butyrophenone neuroleptics like haloperidol.