What is the pathophysiology of malaria in pregnancy?

What is the pathophysiology of malaria in pregnancy?

Malarial infection during pregnancy results into infiltration of the parasite-infected RBCs to the intervillous space of placenta resulting into exacerbated inflammatory response. High inflammation causes oxidative stress-induced apoptotic cell death in the placenta.

What is malaria explain its life cycle pathogenesis and diagnosis of malaria?

The malaria parasite life cycle involves two hosts. During a blood meal, a malaria-infected female Anopheles mosquito inoculates sporozoites into the human host . Sporozoites infect liver cells and mature into schizonts , which rupture and release merozoites .

What are the stages of malaria?

Individuals who are repeatedly exposed to malaria develop antibodies against many sporozoite, liver-stage, blood-stage, and sexual-stage malaria antigens.

Cerebral malaria,with abnormal behavior,impairment of consciousness,seizures,coma,or other neurologic abnormalities

  • Severe anemia due to hemolysis (destruction of the red blood cells)
  • Hemoglobinuria (hemoglobin in the urine) due to hemolysis
  • What are the causes and effects of malaria?

    swelling of the blood vessels of the brain,or cerebral malaria

  • an accumulation of fluid in the lungs that causes breathing problems,or pulmonary edema
  • organ failure of the kidneys,liver,or spleen
  • anemia due to the destruction of red blood cells
  • low blood sugar
  • What are the statistics of malaria?

    reducing malaria case incidence by at least 90% by 2030

  • reducing malaria mortality rates by at least 90% by 2030
  • eliminating malaria in at least 35 countries by 2030
  • preventing a resurgence of malaria in all countries that are malaria-free.
  • Which agent is the cause of malaria?

    Uninfected mosquito. A mosquito becomes infected by feeding on a person who has malaria.

  • Transmission of parasite. If this mosquito bites you in the future,it can transmit malaria parasites to you.
  • In the liver.
  • Into the bloodstream.
  • On to the next person.