Table of Contents
What is 4 aminobiphenyl used for?
4-Aminobiphenyl has been used in the past as a rubber antioxidant, as a dye intermediate, and in the detection of sulfates. It is reportedly used as a model carcinogen in mutagenicity studies and in cancer research (NTP, 2005; O’Neil, 2006; HSDB, 2009).
Is biphenyl an Amine?
It is an amine derivative of biphenyl. It is a colorless solid, although aged samples can appear colored. 4-Aminobiphenyl was commonly used in the past as a rubber antioxidant and an intermediate for dyes….4-Aminobiphenyl.
| Names | |
|---|---|
| ECHA InfoCard | 100.001.980 |
| EC Number | 202-177-1 |
| KEGG | C10998 |
| PubChem CID | 7102 |
Is benzidine specific for blood?
Several presumptive tests have been described for blood stains recognition [1], [2], [3], and one of the most used is Benzidine and its derivative Tetramethylbenzidine (TMB) [4]. Both reagents have similar sensitivity, specificity, and stability [5].
What is a benzidine reagent?
Benzidine is a grayish-red, yellowish or white colored, very toxic, crystalline aromatic amine that darkens when exposed to air and light. Benzidine has been widely used for the detection of blood and as a reagent in the manufacture of dyes.
Is biphenyl a solid at room temperature?
Biphenyl is a highly toxic compound with a pungent smell. It is a solid at ambient temperature with a relatively high sublimation pressure.
Why benzidine test is done?
The benzidine test is most commonly used for the detection of blood in the feces, and was therefore singled out for investigation.
What is a confirmatory test for blood?
Confirmatory tests for blood include identification of blood cells under a microscope [Shaler, 2002], crystal tests such as the Teichman and Takayama tests [Shaler, 2002; Spalding, 2003], and ultraviolet absorption tests [Gaensslen, 1983].
What is the purpose of benzidine test?
How do you perform a benzidine test?
Pipet 100 mL urine into a 180-mL glass bottle. Start a blank control urine sample (100 mL) and two control urine samples (100 mL) spiked with benzidine (0.3 to 1.0 µg) at this point. 5. Add 0.2 g NaCl to the pH-adjusted urine.
What is the limitation of benzidine test?
Benzidine-based tests (e.g., Hematest) have been virtually eliminated from use because of their excessive sensitivity, which results in a high frequency of false-positive reactions, as well as the carcinogenicity of the reagent.
How is a benzidine test performed?
of glacial acetic acid in a clean test-tube, thus obtaining a 0-5 per cent, solution of benzidine hydrochloride. Then either the examining finger of a rectal glove or a clean orange-stick dipped in a faecal specimen is smeared on white filter-paper, and a little of the benzidine solution is poured over the smear.
What is confirmatory diagnosis?
Confirmatory tests are also called diagnostic tests. They confirm or rule out a medical condition in an individual with concerning symptoms or an out-of-range screening result.
What is a false positive in forensics?
A false report or false positive error occurs when two different samples are mistakenly ‘matched’ – whether as a result of coincidence, a faulty or misapplied criteria for determining a ‘match’, confusion, contamination or degradation of the sample [26].