Which type of osteosarcoma has better prognosis?
As for tumor location, several studies have reported the consistent conclusion that osteosarcomas of the extremities have a better survival than the axial osteosarcomas [12,13]. However, others have described a lack of association between tumor site and prognosis [14].
What is small cell osteosarcoma?
Small-cell osteosarcoma, a subtype of osteogenic sarcoma, consists of sheets of round cells that produce an osteoid matrix. It may be confused with Ewing sarcoma if the osteoid matrix is not included in the biopsy.
What are small round blue cell tumors?
Desmoplastic small round cell tumors (DSRCTs, sometimes also referred to as small blue round cell tumor) are a type of sarcoma that usually develops in the belly or pelvis. They are most often found in white teenagers and young men between age 10 and 30. DSRCTs may cause pain or a mass in the belly.
Is osteosarcoma round cell?
Round cell tumors of bone are a divergent group of neoplasms that largely constitute Ewing sarcoma/primitive neuroectodermal tumor, small cell osteosarcoma, Langerhans cell histiocytosis, mensenchymal chondrosarcoma, and hematopoietic malignancies including lymphoma and plasmacytoma/myeloma, along with metastatic round …
What is malignant small round cell tumor?
Malignant small round cell tumors (MSRCT) is a term used for tumors composed of malignant round cells that are slightly larger or double the size of red blood cells in air-dried smears. [1] This group of neoplasms is characterized by small, round, relatively undifferentiated cells.
Does osteosarcoma respond well to chemo?
Since the introduction of chemotherapy into the multi-modal treatment regimen of high-grade osteosarcoma, its prognosis has impressively improved, with long-term survival being achieved in two-thirds of all patients.
Can osteosarcoma go into remission?
Complete surgical remission (CSR) is the best predictor of overall survival (OS) for patients with metastatic osteosarcoma.