Table of Contents
How do you convert to morphine equivalents?
Use the formula: Strength per Unit X (Number of Units/ Days Supply) X MME conversion factor = MME/Day.
What is Endone equivalent to?
Endone 5mg x 6 = 30mg of oral Oxycodone in 24hrs. Total oral Oxycodone requirement in 24hrs is 60+30mg = 90mg. Using Table A of guideline to convert to oral Morphine equivalent factor is 1.5. Therefore 90 x 1.5 = 135mg of oral Morphine equivalent.
How do you do opioid conversions?
Determine equivalent daily dose of new opioid by dividing the calculated MMEs of current opioid by new opioid’s conversion factor. Reduce this amount by 25-50% and then divide into appropriate intervals.
How do you convert morphine IV to morphine?
Example: Change from 90 mg q12 Extended Release Morphine to IV Hydromorphone as a continuous infusion.
- Calculate the 24 hour current dose: 90 Q12 x 2 = 180 mg PO Morphine/24 hrs.
- Use the equianalgesic ratio of PO to IV morphine: 30 mg po Morphine = 10 mg IV Morphine.
What is the conversion factor of morphine to fentanyl?
Assumption two 3,11: morphine (oral) 2 mg = transdermal fentanyl 1 mcg/hour. ‘Breitbart method’ morphine (oral) 50mg = transdermal fentanyl 25 mcg/hour. (x /30) * 50 = 0.6 or 50x = 18 –> x = 0.36 (conversion factor) Conversion from these dosage forms are 1:1 but require special handling.
How do I convert 60 mg of morphine to morphine (IV)?
Morphine (oral) 1 30mg 1. To convert 60 mg of Morphine (sc) 2 to 1 15mg oral Morphine to Morphine (iv) 3 to 1 10mg subcutaneous Morphine Diamorphine (sc) 3 to 1 10mg divide by 2 to give 30 mg. Oxycodone (oral) 1.5-2 to 1 15-20mg Oxycodone (sc) 3 to 1 10mg 2.
How do you calculate breakthrough dose of morphine?
The breakthrough dose of any opioid except fentanyl should be one sixth of the total daily dose . See note below on renal failure. Morphine (oral) 1 30mg 1. Morphine (sc) 2 to 1 15mg oral Morphine to Morphine (iv) 3 to 1 10mg subcutaneous Morphine Diamorphine (sc) 3 to 1 10mg divide by 2 to give 30 mg.
How do you convert morphine to oxycodone?
Morphine (sc) 2 to 1 15mg oral Morphine to Morphine (iv) 3 to 1 10mg subcutaneous Morphine Diamorphine (sc) 3 to 1 10mg divide by 2 to give 30 mg. Oxycodone (oral) 1.5-2 to 1 15-20mg Oxycodone (sc) 3 to 1 10mg 2. NB. At lower doses, fentanyl conversions are less accurate.