What is the difference between clopidogrel and Brilinta?
Bottom Line: Brilinta (ticagrelor) appears to be slightly more effective than Plavix (clopidogrel) in reducing the percentage of CV death, MI or stroke in the first year of treatment. Brilinta patients had more breathing difficulties as a side effect compared to Plavix patients.
Why is ticagrelor used in ACS?
Ticagrelor has been acknowledged as a new oral antagonist of P2Y12-adenosine diphosphate receptor, as a strategy with more rapid onset as well as more significant platelet inhibition function in acute coronary syndrome (ACS) patients.
Which is best Plavix or Brilinta?
The findings come from a sub-study of the PLATO trial, which showed that Brilinta works better than Plavix at preventing heart attacks, strokes, and deaths from heart disease in people with acute coronary syndrome (ACS).
When should you not use ticagrelor?
Ticagrelor should not be used in patients with active pathological bleeding or a history of intracranial hemorrhage. Clinicians should not prescribe ticagrelor for patients who are expected to undergo urgent CABG surgery. If possible, ticagrelor should be discontinued for at least 5 days before any surgery.
Can I take clopidogrel instead of ticagrelor?
Importance Guidelines currently recommend ticagrelor over clopidogrel for patients with acute coronary syndrome (ACS) based on randomized clinical trial data in which ticagrelor reduced major adverse coronary events (MACE) vs clopidogrel but increased bleeding and dyspnea.
Can you take ticagrelor and clopidogrel together?
Using ticagrelor together with clopidogrel may increase the risk of bleeding. Talk to your doctor if you have any questions or concerns.
When is Brilinta preferred over Plavix?
Brilinta (ticagrelor) is now preferred over clopidogrel for the management of patients with acute coronary syndrome (ACS) who have received a coronary stent and in non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) patients treated with medical therapy alone (Class IIa LoE: B-R).
When should I stop using ticagrelor?
You’ll usually need to take ticagrelor for up to 12 months. Your doctor may want you to continue taking it after the 12-month course has finished. If so, you’ll take ticagrelor at a lower dose of 60mg a day for up to 3 years.
Can you take ticagrelor long term?
New data supports long-term efficacy of ticagrelor in patients up to five years following a heart attack.