What is GastroPlus software?
GastroPlus is a mechanistically based simulation software package that simulates intravenous, oral, oral cavity, ocular, inhalation, dermal, subcutaneous, and intramuscular absorption, biopharmaceutics, pharmacokinetics, and pharmacodynamics in humans and animals.
When did Simulations Plus go public?
1999
In 1999, Simulations Plus listed on the NASDAQ (American Stock Exchange) under the symbol SLP.
Is PK SIM free?
PK-Sim® and MoBi® for PBPK and Quantitative Systems Pharmacology. Reliable, powerful and easy-to-use modeling & simulation tools for pharmaceutical and other life-sciences applications. Qualified and accepted by the scientific community including academia, regulatory agencies and industry. Available free to everyone.
What is PBBM modeling?
Physiologically based biopharmaceutic (PBBM) models cover a recent field of research by the integration of in vitro dissolution experiments into PBPK models to predict the behaviour of the oral formulation in vivo and verifying whether the dissolution method of the pharmaceutical product is biopredictive or clinically …
What does simulation plus do?
Simulations Plus, Inc. develops absorption, distribution, metabolism, excretion, and toxicity (ADMET) modeling and simulation software for the pharmaceutical and biotechnology, industrial chemicals, cosmetics, food ingredients, and herbicide industries.
Which softwares are used for pharmacokinetics?
The best software to be used for individual pharmacokinetics is T.D.M.S in which, we can apply Bayesian and least square method for curve fitting and it can be used for both linear and non-linear pharmacokinetic data.
What is Pksim?
PK-Sim® is a comprehensive software tool for whole-body physiologically based pharmacokinetic modeling. It enables rapid access to all relevant anatomical and physiological parameters for humans and the most common laboratory animals (mouse, rat, minipig, dog, and monkey) that are contained in the integrated database.
Is Phoenix WinNonlin free?
WinNonlin users can request a free 60-day trial by contacting +1 (919) 852-4685 or visiting www.certara.com/answer.
How do you design a simulation?
Key Steps in Designing a Simulation
- Select a historical event or system for the simulation.
- Determine the key processes in the historical event or system.
- Determine the participants’ roles.
- Determine the participants’ goals.
- Determine the tools available to the participants.
How much does Phoenix WinNonlin cost?
Cost – $1,500 (Academia $750)
What is WinNonlin software?
WinNonlin is a pharmacokinetic software package that has grown and evolved over the past 20 years. The most familiar versions of WinNonlin (v3 – v5) were stand-alone Windows-based software packages used to perform non-compartmental analysis and single subject non-linear model fitting.
What can GastroPlus do for You?
You provide the (limited) data, GastroPlus provides everything else: Flexible licensing models. Ask us for more details. Integration with our other tools. Seamlessly define inputs for your PBPK & PBBM models using the top-rated quantitative structure-activity relationship (QSAR) models from ADMET Predictor®.
Who uses the GastroPlus PBPK platform?
The GastroPlus PBPK modeling and simulation platform has been utilized by companies across various industries and departments since 1998. Some of the routine applications include: … and more! Read about various case studies by scanning the peer-reviewed publication list!
What are the IM and CR dosage forms of GastroPlus?
GastroPlus now provides two intramuscular (IM) dosage forms, both of which assume that drug is injected into the muscle tissue. One of these is an immediate release (IR) dosage form, with the other treated as controlled release (CR).