Table of Contents
What is Chronotherapy used for?
Chronotherapy aims to restore the proper circadian pattern of the sleep-wake cycle, through adequate sleep hygiene, timed light exposure, and the use of chronobiotic medications, such as melatonin, that affect the output phase of circadian rhythms, thus controlling the clock.
What is chronomedicine?
Chronomedicine may be conceptualized as dealing with the prevention, causation, diagnosis, and treatment of diseases in humans with a particular focus on the role “time” [Greek: chrónos] plays in our physiology, endocrinology, metabolism and behavior at many organizational levels.
What is Chronotherapy and how is it useful in determining when to administer drugs?
Chronotherapy is a relatively new method of treatment that is based on the premise that administering medications at different times of the circadian cycle will minimize side effects and maximize therapeutic effects (Fig. 103-2).
Is DSPS curable?
With your doctor’s help, you can get your sleep back on track. Treatment aims to change your body clock with bright light therapy, melatonin, and good sleep hygiene. It might also involve adjusting your sleep and wake times. DSPS is most common in teenagers, but it can happen at any age.
Is chronobiology a pseudoscience?
Thus, in the public eye, chronobiology has moved completely from a pseudoscience to one of the most intensive areas of scientific investigation in the last 40 years.
What is meant by chronobiology?
Chronobiology is a field of biology that examines timing processes, including periodic (cyclic) phenomena in living organisms, such as their adaptation to solar- and lunar-related rhythms. These cycles are known as biological rhythms.
How do you know if you have DSPS?
If you have DSPS, you can’t fall asleep at a socially acceptable bedtime. Instead, your sleep is delayed by at least two hours. This happens even when you’re tired. The delay can make you wake up later, which might interfere with work, school, and other daily routines.
What is a chronotherapeutic drug delivery system?
The purpose of writing this review on chronotherapeutic drug delivery systems (ChrDDs) is to review the literatures with special focus on ChrDDs and the various dosage forms, techniques that are used to target the circadian rhythms (CR) of various diseases. Many functions of the human body vary considerably in a day.
What is the best time of day to use chronotherapy?
Chronotherapy (sleep schedule) can be used with a progressive phase advance around the clock until the desired bedtime is reached.48 For most patients, this is not practical. The most common treatment is bright light in the evening from 7 to 9 pm ( Table 26–7 and Boxes 26–9 and 26–10 ).
What are the different technologies used in drug delivery?
These technologies include Contin® , Chronotopic®, Pulsincaps®, Ceform®, Timerx®, Oros®, Codas®, Diffucaps®, Egalet®, Tablet in capsule device, Core-in-cup tablet technology. A coated drug-core tablet matrix, A bi-layered tablet, Multiparticulate-based chronotherapeutic drug delivery systems, Chronoset and Controlled release microchips.
What is the business model of the drug delivery device company Bespak?
Bespak develops and manufactures drug delivery devices, focusing on inhaler and auto-injector technologies. Part of its business model involves helping customers commercialize their own designs for drug delivery devices as well as developing proprietary designs for its own devices.