What drug class is dipivefrin?
Dipivefrin is a member of a class of drugs known as prodrugs. Prodrugs are usually not active in themselves and require biotransformation to the parent compound before therapeutic activity is seen.
Is dipivefrin a cholinergic?
PROPINE® (dipivefrin) does not produce miosis or accommodative spasm which cholinergic agents are known to produce.
Is epinephrine used for glaucoma?
Because epinephrine is devoid of accommodative and miotic effects, is administered twice a day, and is accompanied by relatively minor complications, it can be used as the initial therapy for primary open angle glaucoma, as an additive to current therapy, and as part of maximal medical therapy for glaucoma.
Why are beta blockers used in glaucoma?
Topically administered beta blockers are the preferred medical therapy for glaucoma. These agents reduce intraocular pressure (IOP), thereby preventing damage to the optic nerve and the subsequent loss of vision.
Can brimonidine cause blindness?
To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed when you are not using the drops. If germs get in the bottle, your eye could become infected. Serious eye infections can cause blindness.
Who should not take brimonidine?
Brimonidine is also contraindicated in patients with hypersensitivity to any component of the medication, and it should not be used in children under the age of 2 because there have been reports of apnea, bradycardia, hypothermia, hypotonia, lethargy, and unresponsiveness in infants receiving brimonidine treatment ( …
What does epinephrine do to the eye?
Epinephrine solution is used for mydriasis (dilation or widening the pupil of the eye) during eye surgery.
What is the drug dipivefrin used for?
Dipivefrin is only found in individuals that have used or taken this drug. It is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops). Dipivefrin is a prodrug with little or no pharmacologically activity until it is hydrolyzed into epinephrine inside the human eye.
What is the generic name for Dipivefrine?
Dipivefrine ( INN) or dipivefrin ( USAN ), trade name Propine among others, is a prodrug of epinephrine, and is used to treat open-angle glaucoma. It is available as a 0.1% ophthalmic solution.
Is Dipivefrine still available in the US?
Dipivefrine. Dipivefrine ( INN) or dipivefrin ( USAN ), trade name Propine among others, is a prodrug of epinephrine, and is used to treat open-angle glaucoma. It is available [citation needed] as a 0.1% ophthalmic solution. It is no longer available in the United States.
Is Propine the same as Dipivefrine?
Dipivefrine (INN) or dipivefrin (USAN), trade name Propine among others, is a prodrug of epinephrine, and is used to treat open-angle glaucoma. It is available as a 0.1% ophthalmic solution.