What is Propess made of?

What is Propess made of?

The Propess pessary contains a synthetic prostaglandin and is placed high into the vagina next to the neck of the womb. The pessary looks like a small flat tampon and has a tape attached which makes it easier to remove if needed.

What hormone is in Propess?

The Propess pessary contains the active ingredient dinoprostone, which is a naturally occurring female hormone also known as prostaglandin. Once inserted into the vagina the pessary will stay there for 24 hours slowly releasing the hormone to ripen your cervix.

Is Propess a dinoprostone?

PROPESS contains the active substance dinoprostone 10 mg and is used to help start the birth process provided that 37 weeks of pregnancy have been completed. The dinoprostone opens the part of the birth canal known as the cervix, to allow the baby through.

What is dinoprostone pessary?

Dinoprostone is one of the synthetic prostaglandins most commonly used to achieve cervical ripening and labour induction, and can be administered as tablets, suppositories, gel (vaginal and intracervical) or as a controlled-release intravaginal pessary.

What is the difference between Propess and prostin?

Propess – The vaginal insert is removed 24 h after the application. It is only to be removed earlier in case of the onset of active labour or at the occurrence of hyperstimulation. Prostin – 3 mg vaginal tablet is placed in the posterior vaginal fornix.

How effective is prostaglandin pessary?

Approximately 75-80% of women will have given birth within 24 hours of having Propess inserted. If you start having regular contractions, we advise you to call the maternity unit to be advised on when to come back in. As your labour progresses the pessary may fall out or be removed by the midwife.

What is dinoprostone made from?

Each insert contains 10 mg of Dinoprostone in 241 mg of a cross-linked polyethylene oxide/urethane polymer which is a semiopaque, beige colored, flat rectangular slab measuring 29 mm by 9.5 mm and 0.8 mm in thickness.

How quickly can a Propess work?

How long will it take? Once the Propess has been inserted Prostaglandin is slowly released over 24 hours and acts in a similar way to the hormone that your body produces when you go into labour naturally.

What is the side effect of dinoprostone?

chills and shivering. increase in vaginal bleeding several days after treatment. chest pain or tightness. skin rash.

Does Dinoprostone hurt?

Are there any side effects? At first, you may have some cramping, backache or a warm feeling in your vagina. It usually takes a few hours before you feel contractions.

What is a dinoprostone?

Dinoprostone Description. Dinoprostone Vaginal Insert is a thin, flat, polymeric slab which is rectangular in shape with rounded corners contained within the pouch of an off-white knitted polyester retrieval system.

How much dinoprostone do you give a pregnant woman?

Dinoprostone Dosage and Administration. The dosage of Dinoprostone in the vaginal insert is 10 mg designed to be released at approximately 0.3 mg/hour over a 12 hour period. Dinoprostone Vaginal Insert should be removed upon onset of active labor or 12 hours after insertion.

What is dinoprostone vaginal insert 10 mg used for?

Dinoprostone Vaginal Insert 10 mg is indicated for the initiation and/or continuation of cervical ripening in patients at or near term in whom there is a medical or obstetrical indication for the induction of labor. Dinoprostone Vaginal Insert is contraindicated in:

What is the rate of release of dinoprostone?

The reservoir of 10 mg dinoprostone serves to maintain a controlled and constant release. The release rate is approximately 0.3mg per hour over 24 hours in women with intact membranes whereas release is higher and more variable in women with premature rupture of membranes.